Easy - let them die of measles. If they chose not to be vaccinated they can choose to die of an easily preventable disease. Then throw a big party celebrating them being gone.
""It was something new and different, and there were a lot of things that were really cool about it: the imagery, the design. Given the lack of sophistication of some of the tools they had to work with, there was a very clever design done to work within the capabilities. The Light Cycles, the Tanks, and the Recognizers were very clever designs. They're super-minimal, but just they're really nice, distinctive, and there were really great art direction choices made about color and camera angles. [Tron] opened everyone's eyes to something they should be watching because it had a lot of potential."
"Look! There! Evil!.. pure and simple, total evil from the Eighth Dimension!" -- Buckaroo Banzai