Comment Re:Should come as no big surprise... (Score 1) 62
Ultraviolet radiation and skin cancer
Ultraviolet radiation and skin cancer
This is probably not surprising since both Leydig cells and Sertoli cells express ACE2. Both Leydig cells and Sertoli cells are found in the testes, where Sertoli cells is a central player in the spermatogenesis, while Leydig cells produce testosterone. ACE2 is the transmembrane protein SARS-CoV-2 uses to enter cells. The expression of ACE2 on these cells was already shown in a study from 2004 published in Endocrinology https://academic.oup.com/endo/... (paywalled).
How did they simulate zero gravity and its adverse effects on the human body??
This has already been done years ago. You can simulate the influence of microgravity http://en.wikipedia.org/wiki/Weightlessness#Microgravity on the cardiovascular system and the skeleton using so called head down bed rest. The idea is if you are laying down at a down tilt of e.g. 5 degrees and are not allowed to stand up or sit up during the experiment you can simulate both the influence on the cardiovascular system and the unloading of the bones.
In the late 1980ies a 370-day-long head down tilt bed rest experiment was carried out in the Soviet Union, which is the bed rest study of the longest duration yet. This study showed that it was possible to counteract the immobilization induced bone loss by doing 1-2 hours of exercise per day combined with treatment with a pharmaceutical (a bisphosphonate, which is part of a group of agents that is currently used for treating/preventing osteoporosis [http://en.wikipedia.org/wiki/Bisphosphonate]). A control group who did not do any countermeasures experienced a significant loss of bone mass after 120 days of bed rest, after which they also stated the same exercise regimen as the other participants and seemed to regain some of the lost bone.
Citation: http://www.ncbi.nlm.nih.gov/pubmed/16235873
(For reasons that is not clear to me this study was not published and the samples were put on storage unanalyzed until we got access to them. We analyzed the bone samples and published them with the original investigators from Russia and France.)
The European Commission disagree with you as they use the term "ban" in their news release: http://ec.europa.eu/news/energy/090901_en.htm
Also, the British thinktank who instituted this are a right-wing one, no doubt plotting to destroy the NHS alongside the Tory allies. So they publish a non-peer reviewed piece of 'research' designed to conclude what they want it to conclude. Bullshit.
The study was published in a journal called Demography http://www.populationassociation.org/publications/demography/. From the journals web page: "Demography is a peer-reviewed journal. All manuscripts considered appropriate for the journal are reviewed externally." Consequently, the research study was actually peer reviewed...
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