I understand why companies are moving away from the idea of removable, normalized-size drives [it's cheaper to make the machine when it's just a daughter-board] but the loss of flexibility really chafes.
There are standards for smaller flash drives, but the situation isn't looking quite universal. One thing that bugs me is the smaller version of SATA in 1.8'' drives; the shared connector between 3.5'' and 2.5'' drives was an incredible improvement over the PATA situation.
Generally, I find it dumb when "desktop" and "mobile" components are artificially segregated by the use of different connectors etc., while it's really the same computer tech underneath. I like to use quiet and low-power stuff for my non-mobile needs, basically because I have to pay for the electricity and listen to the fans myself. Also, you'd think it were cheaper to build fewer different models of everything. SATA for 2.5'' and 3.5'' was a brief moment of sanity, and now we're in the same mess again.