Well, I started out with a triple major in Physics, Math and Computer Science, but eventually dropped out for a while and became a Hippie. I didn't actually pick up my Physics from the Principia, but I did go to a Jesuit University and actually had to read it. I cannot adequately express how valuable this book has been to me.
Dean Kamen dropped out of school, went to the library, studied Newton's Principia, and went on to be an awesome inventor and thinker.
Eli Goldratt used the thinking processes in the Principia to turn USA manufacturing and business methods on their respective heads. Read his books, "The Goal", "It's not Luck" and "Critical Chain" for some really interesting examples of thinking. He wrote a terrific book, "The Choice" https://www.amazon.com/Choice-... which clearly describes how useful Newton's methods are.