The real issue is that the packaging process used to create vaccines in quantity is a process where you mix a tank of mRNA with a tank of other stuff and get a tank of lipid nanoparticles. Getting different mRNA in each dose means you only get one patient's vaccine per time you start and stop the machine. There's also a step where one copy of mRNA is used to make a macroscopic quantity of copies in a bioreactor that needs to be flushed in between different sequences, but can just run when making enough of the same thing for a large population. It's likely that the cost for each different sequence will come down if it's worth designing and building equipment that switches every dose, but there's an intermediate time between proving that the treatment is useful and being able to provide it in a cost-effective way.

Jesus Fucking Christ. It's 2026, Trump has been putting his boot on the necks of major networks and studios for a year and a half now. I realize you probably fell into a coma in 2016, but ten years later, the free press, regardless of what you think of it, or fair you imagine it is, is under direct assault. Fuck off with the "MSM" bullshit and grow the fuck up.

It's clearly all the superfans who hear that there's a new album and immediately drive into their local record store. (Rather than doing the sensible, calm thing and entering the store on foot.)

The problem with this argument, from the shop's point of view, is that the UK is in the middle of a shoplifting epidemic. The policing resources simply aren't there to deal with small scale (or even flagrant and much larger scale) shoplifting. It now seems to be rare for police officers to attend reports of shoplifting at all. And so effectively shoplifting becomes legalised, which is obviously hurting the big chain stores financially and potentially devastating for smaller shops.

Shops are trying to find some way to respond to this to protect themselves. They typically tell staff, even security staff, not to get physical with shoplifters as they walk out, not least because the risk of something worse happening and the business becoming liable for it is significant. But then the shoplifters know this and some of them will just walk in and openly empty a shelf into a bag and walk out again without paying because they know no-one will try to stop them.

Shops also know that our court system is completely overwhelmed at the moment and there is little chance of bringing any successful civil action to recover damages from shoplifters who aren't even being arrested by the police and put through the criminal justice system.

So what do they have left? Basically, they're trying to spot the "usual suspects" and refuse them entry in the first place, which is a less risky proposition in terms of potential for physical violence and quite effective because a lot of shoplifting is done by the same people, or they're trying to make it more physically difficult to steal goods, for example by using locking systems or keeping high value items behind counters where customers can't just pick them up. But these systems aren't perfect, far from it, and what we're discussing here today is one of the significant problems.

Obviously this kind of technology can have very bad consequences, as we see here. I don't think it should be used if it's not highly reliable, given the potential harm done in cases where it gets something wrong. But I do have some sympathy with the shops who are looking for something -- anything -- to reduce the threat they're facing because the rule of law has failed in retail settings.

Even if they don't pollute all the time, consider when a "power emergency" will be most likely. One common situation is when there is a stagnant heat dome sitting on the area forcing everyone to crank up their A/C.

Then the data centers will fire up their gas and diesel generators with short exhaust stacks, and with no wind all those fumes will just linger in the general vicinity.

The publishing industry is demanding this via lawsuits. Their position: you can not make copies. So if the book is turned into electronic form, then the physical copy must be destroyed. Only one instance of the text can exist. This has been a fight now in multiple lawsuits where AI companies were forced into paying for a physical copy of every book they scanned.

Gee, if a counterfeit lithium ion battery peddled by Amazon burns your house down, you get to sort it out in small claims court.

Or else let some guy whose salary ultimately comes from Amazon decide whether they're liable.

For me the visualization of direct collapse black hole formation is that there's still a huge mass of gas falling in, at the boundary of the new black hole nearly dense enough to direct collapse itself. The blowback would compress the inflow over the density edge and you get a whole cloud of black holes.

People thought that I was crazy for wearing this sharply angled black stealth suit.

Who's laughing now?

It's pretty cool that they're seeing where the supermassive black holes come from. The models of what's happening in there must be amazing.

On the contrary, I think most of your comment is as relevant as ever. A carefully designed UI is still better for almost any specific task than what "agents" will produce. It will probably be more efficient to describe what you want precisely enough to get it right. It will not be undermined by problems like non-repeatability, non-determinism and hallucinations that are inherent in LLM-backed agents.

Agents can be quite effective at getting something that seems about right, as long as you don't care too much about the details. And of course they get there much quicker than doing it manually as a human. This is useful for some tasks, and why they have become popular.

Unfortunately, it turns out that for many of the things we really care about, "about right" doesn't cut it. Right now, today, the software industry is already being overwhelmed by AI slop. It's hard to believe, but it's still only been a few months since agentic development processes arrived on the scene. And yet after just those few months of management trying to replace real developers with agents, we can see the slow-motion train wreck happening right before our eyes. And in return, where are the new applications that radically improve on what we had before thanks to all this added "productivity"? If this tech is going to change the world as the AI tech bros and the sycophantic CxOs kneeling at their feet would have us believe, where's my flying car?

Imagine a Beowulf cluster of AI-generated cybersecurity nightmares...

Whether we like it or not, whether we use Windows or not, Microsoft is going to insist on adding the tax whether the PC comes shipped with Windows or not. This is illegal bundling, Microsoft has essentially ignored prior rulings, and it's pretty much a certainty the courts will be fine with this.

Time to turn in your geek card. A "watt" is a unit of *power*. People pay for *energy*. Energy = power X time.

Electricity is often sold in energy units called kWh (which is 3.6 megajoules). At a retail price of 20 cents/kWh, five dollars of electric ital energy is 25 kWh.

With a power consumption rate of 1000 kW, that amount of energy is used in 90 seconds. Presumably, the 1MW peak power rate was only used briefly, just like a car with a 300hp peak power engine usually cruises around only generating a couple of dozen hp.

It is. The fact that our dominant desktop operating systems are still using security models from last century is probably the #2 disaster of modern tech security, coming in just behind so much software with potential security implications still being written in languages like C and C++ at #1. And the understandable yet still deeply regrettable reason for both disasters is the same: momentum.