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Comment Re:who are cyclists? (Score 1) 203

Man, I thought this was a pretty simple concept, obviously I was wrong. My post comes from my experiences biking to work, and then deciding that other things were more important, so I stopped. These are really simple things like picking my kids up from school, or being able to meet at a client's business. Yes, I absolutely could have found other people to handle those things, but it was more important to me to be able to rely upon myself alone in those situations than it was to bike to work.

The point of TFA was that biking lowers stress. I think that accepting stress into your life reduces your ability to bike.

Comment Re:who are cyclists? (Score 1) 203

Yeah, you clearly have a different way of life than I do, and you obviously have made great choices for you regarding where you live and what you do.

The idea that work is one place, where you're not asked to go to other places during the day, or help shuttle people around, is quite a nice thing. Maybe "flexible working hours" is not the right phrase, but something more like "flexible work requirements." I run my own business, which is great for me, but not for biking. It's not ok for me to put off going to a client to swap out hardware, or to not go meet a potential investor who's across town and is available to meet on short notice. My car carries spare work hardware, kid's snacks and toys, and a backup suit. It all gets used pretty regularly.

I have biked to work at a previous job, It was absolutely wonderful, and I loved it. My personal and professional ambitions grew, and I chose to sacrifice an ability to be car-free. My point is simply that the lack of biking is not what generates stress in life, it's the stress of life that prevents biking.

Comment who are cyclists? (Score 2) 203

People who cycle to work are people who:
1) Don't need to personally take care of their children in an emergency
2) Live close to work
3) Have flexible working hours and standards
4) Have a nice enough job to support an office and a place to put a bike

In short, cyclists have a lower stress life. I would argue very strongly that cycling to work is the result of a lower stress life, not the cause. It is not a lifestyle that most of us can afford for reasons that have nothing to do with cycling.

Comment Re:Start by banning one time keys (Score 1) 123

Introductory courses are hard because everyone has different ideas of where to start.

At high levels, international standards have existed for a long time. Decades ago, in the height of the Cold War, a Russian series of physics textbooks was the standard worldwide. It's still used today. It has some generic physics names, but is referred to as "Landau and Lifshitz." If we could use a Soviet authored standard set of physics books in the US in the 1960s, we could probably use international standards today as well.

I think the problem we have is that most people don't like being told what to do. If you're a school board member or a university trustee, you're not going to want to hear that your philosophy of how education should be done is not the standard, and that's just too bad.

Landau and Lifshitz is notoriously difficult for starting students, and its adoption led in part to the design of undergraduate physics education as a primer for graduate school rather than training to be a working scientist. This may sound irrelevant and minor, but that is a very different philosophy than most science and engineering fields, and it was just too bad for educators and students who thought BS Physics holders should be able to work in physics.

More on topic... many physics books (including Landau and Lifshitz) are available online already. Others are available at very reduced cost through Dover publishing. Often, the US government efforts to "modernize" physics textbooks (teaching 100 year old physics) pay professors to write new and expensive textbooks. When the granting agency that supplies all of your research funding recommends a textbook, it's very hard to say "no." An amazing amount of the publishing business in science is driven by unintended consequences of granting agency policies.

Comment let's take a step back here (Score 2, Interesting) 447

What is authorized and un-authorized use? Has Google made any effort to limit use to only the owner, or have they optimized to allow use by anyone who can talk to the device? If there's no authentication, log-in, or physical controls, there's no permission needed to use the device. What does the owner need to do to keep other people from using the device? Turn it off.

Comment not Apple's strength (Score 5, Informative) 94

If this is real, Apple is very much behind the times when it comes to both sensor technology and understanding of the medical device market. Trying a spectroscopic approach (which appears to be the case) is way out of date, that's a generation behind even the FDA cleared tests, and isn't going to compete with the new generation of sensors being developed now.

There are several approaches to continuous monitoring of glucose, going back more than 10 years.

Many of these technologies, particularly the non-invasive ones, are more available outside the US than inside. This has more to do with the way medical device manufacturers are paid than any technical limitation. Bluntly, being in the glucose monitoring business is a great way to lose a lot of money quickly. Yes, the market is big, but it's brutal. Apple's strength is not dominating low margin, highly regulated markets.

Comment Re:Between Uber and Google, so.. (Score 1) 35

If you work for any company (or these days, a university) doing technology development, you're required to sign IP assignment agreements.

A good organization will list the specific IP being held as a trade secret as part of your exit agreement when you leave. The best situation for everyone is clarity and clear ownership of very specific items.

A bad organization will try to blanket claim everything it can extending past the time of employment. The trick here is, you don't have to sign those agreements. It's all a negotiation. I've worked at places where I did not sign the IP assignment agreement, and while the lawyers hated it, it's their own damn fault for crafting an agreement that was overly broad.

Comment the big problem here is Google's hypocrisy (Score 1) 238

We can all debate until we're blue in the face whether the gender gap between an average woman and an average man is the product of perfectly reasonable individual choices or societal pressure.

What's really not debatable is that Google leadership has actively advocated for more oversight of business by the government, while simultaneously ignoring regulations when it comes to their own business.

Every other large government contractor has to file these reports. Every other large government contractor is judged by the labor department rules, not by their internal metrics.

This is why government oversight sucks. Sometimes they're looking at things that don't make sense, sometimes it's counterproductive. Sometimes it's necessary. If Google really thinks the Labor Department approach is wrong, they should have been working their very significant political connections to change the rules to the right policy. Instead, they created political cover for themselves, and were happy to have everyone else subject to rules they disagreed with.

Comment it's easier for them (Score 1) 339

I think enough people here have worked in the kind of positions charismatic narcissists tend to inhabit to understand this. If you're the kind of person who thinks it's possible, even likely, that people around you have better ideas than you do, being responsible for deciding which idea is best is difficult. (If you really think it's easy to lead a group of people, guess what kind of leader you are...)

Gathering ideas from people around you and making sure credit goes to those people is the right way to run any organization, large or small. But it's much easier to shoot for action without argument, if you have the smile to get it. I think the result is that humble leaders don't last as long, they burn out or decide to change their focus more often.

Comment Re:What is the goal of the startup (Score 1) 140

This is the comment to read here. There are a lot of really bad startup companies out there, and very few good ones. Assuming you want to make a good one, this is all great advice.

There's a lot that goes into a good idea, and no one else believes your idea is good. The difficult part is convincing people your idea is good, no matter how obvious it is to you. Next: plan, plan, plan. Develop a thick skin, and get used to paying other people more than what you're making.

Comment how to lower the cost of drugs (Score 1) 311

As multiple other people here have posted, the pharma industry spends at least $2.5B in R&D per new drug. Also, almost all of that is spent in the US, where the vast majority of new drugs are researched. To attract talent, pharma companies generally put their R&D in desirable places to live, have nice facilities, and pay good salaries. When you have a team of ~1000 scientists and doctors working for 5-10 years on a drug, you're going to spend a LOT of money. Just the cost of capital to develop a drug is staggering. The easy answer is to pay people less, and convince them to work in cheaper facilities... The rest of the world tried that and now virtually all the drugs are developed in the US.

One way to do fix this is to focus on spinning out R&D efforts as startup companies. This places the financial risk on the scientists doing the work, but also gives them much greater rewards for success, and an incentive to keep costs low. That's the giant problem with pharma development and marketing right now: no one has any real incentives to keep the costs down.

There are R&D grants for orphan drug development, and there are patient advocacy groups that help with clinical trials. We need to be able to get to a future where a "successful" small pharma effort is one with $5-10M of annual revenue.

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