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Comment Hardly Surprising (Score 5, Interesting) 54

Countries like the USA, unnecessarily feeding cattle with antibiotics for profit.
Adulterated medication being sold in corrupt countries with lower dose
Overprescribing and ineffective water treatment, meaning waterways contain low dose antibiotics
Patients not completing their medication

It is no wonder that resistance is developing quickly

Comment That seems correct to me (Score 4, Informative) 29

We have loads of PHP applications in use where I am that will need to remain in service for the forceable future, we have the developers on the team and that is what they know best. We would like to build new projects in something more modern like Go, but changing is hard. Some new small projects are done in Go, and we see PHP as something that we will gradually move away from, but these things don't happen overnight.

Comment Re:In the USA, yes (Score 3, Insightful) 185

You seem to be making two incorrect assumptions

1. It costs the same to educate a student in China as it does in the USA, not the case, the profit driven school system in the USA results in significantly higher costs than those in China.

That I am blaming Trump. Also incorrect, the US education system has created a population where the majority are incapable of critical thinking and rational decision making, hence why someone like Trump could ever get elected. This would not happen in most other developed democracies.

Comment In the USA, yes (Score 4, Insightful) 185

In the USA, there has been under investment in education and things that benefit society as a whole. Meanwhile China has invested heavily in education, sending their brightest students to the best universities all around the world.

One of these nations is growing and gaining influence globally, the other elected an orange clown as it’s president and is the butt of jokes the world over.

Comment Worst Drivers & Riders (Score 1) 54

Uber, JustEat etc are among the worst drivers and riders there are, every day I witness them committing traffic violations. Running red lights, driving in bus lanes, on sidewalks, making illegal turns, all daily occurrences. So we'll soon see these autonomous vehicles driving like a deranged uber driver.

Comment Time to take IT seriously (Score 4, Interesting) 92

Companies like this will never learn, they bring in highly paid IT managers with their MBAs, whose job it is to micro optimise at the expense of the macro function. They listen to the BS being spouted by the sales drones from companies selling IT services, drop all their skilled IT staff and outsource to the cheapest providers. They need to stop treating IT as an expense like their energy bills and start treating IT as a strategic advantage to the company. Having a skilled IT workforce has a cost, but it results in a coherent IT environment and that is reflected in the results of the company.

Comment Idiots do idiotic things (Score 5, Insightful) 146

This is simply a case of Idiots doing idiotic things.

The first problem e-bike or not is people gettIng on their bike for the first time in years with a level of confidence that far exceeds their ability, due to being out of practice. The do things like underestimate stopping distances at speed, as well as being unaware of dangers, when you cycle regularly you are on the lookout for danger.

The next problem is simply there are far too many inconsiderate people in urban environments. Mindless pedestrians looking at their phones instead of where they are going stepping out in front of you. Delivery van drivers and parents taking their kids to school in their 4x4 using cycling lanes as parking spaces. Cyclists wobbling all over the place and ignoring traffic laws, riding on pavements, the wrong way down cycle lanes and most frustrating ignoring red lights and failing to give way to pedestrians at crossings.

Finally there is a massive problem with illegal bikes, with high powered motors, that propel the bike at speeds far higher than the legal limit as well as not requiring the rider to pedal. The worst offenders are food delivery riders, that get paid by the delivery, so they zoom around at top speed, ignoring all tules, going on pavements to get past stationary traffic with earbuds in and often using their ordering app on a phone attached to the handlebars. The police do nothing, they even get their doughnuts delivered to their office by these riders and do nothing. Regular confiscation of these illegal bikes would be a good starting point.

Comment Bad recommendations (Score 2, Insightful) 84

Honey is no better than sugar, what terrible advice

We know that refined sugar in whatever form is bad for our health, particularly causing diabetes and contributing to heart disease. It doesn't matter what form the sugar takes, corn syrup, cane sugar or honey, just because it is 'natural' does not make it any better, instead of being refined by humans in a factory, honey is sugar that is refined by bees.

So if sweeteners really do cause a decline in cognitive ability (rather than simply being a correlation) then perhaps sweeteners are not a good choice as an alternative to sugar, instead people need to look at ways of reducing their sugar intake and get used to food that isn't quite so sweet. Unrefined sugar that is found in foods like fruit do not create the glycemic spike that refined sugars do

The trouble is things that are bad for us are generally enjoyable, and nobody likes being told what they should be doing, especially when they know full well that their choices are harmful. If people could be convinced with the facts people wouldn't drink alcohol, smoke or take recreational drugs, all things that are far worse than sugar, but still very popular among people

There is no easy fix, it takes people to want to make these lifestyle choices.

Comment Re:Lots of medications and procedures are guess wo (Score 1) 126

Raised LDL is not the only factor in heart disease, there is an inflammatory component to it as well. Some people have elevated LDL but very little stenosis, others have normal LDL but still suffer stenosis. What is known without doubt is that lowering LDL levels in MI patients is directly responsible for a significant reduction in repeat events. The results are different in the general population, simply because only those people that suffer from stenosis will see any improvement, statins do not stop people from having hear disease, they slow down the development of stenosis, reducing the likelihood of a repeat event and extending the time between events. It is also understood by cardiologists that LDL is currently the best target for treatment, however Lipoprotein A has a more significant impact. We have not traditionally tested for Lipoprotein A because there has been no effective way to treat it, that is changing now though, there are some positive steps towards lowering Lipoprotein A levels that it is hoped will have an even greater impact than statins have.

Comment Re:ACE inhibitors (Score 1) 126

ACE Inhibitors and ARBs are not primarily prescribed to lower blood pressure, although that is a bonus because lower blood pressure does result in fewer cardiovascular incidents. ACE Inhibitors are principally prescribed in an attempt to reduce Cardiac remodelling. This theory is that where the muscle cells have died scar tissue forms, because your heart has to work harder to compensate for the reduction in blood flow greater stress is places on the scar tissue. This causes the heart to lose its usual hear shape and become more rounded.

Why is this a problem, because blood that pools in the ventricle can clot and that clot can then find its way to somewhere you don't want it like your brain or lungs.

Comment Re:Retesting old dogma... (Score 1) 126

It has been known for a long time that beta blockers offer no benefit to patients with preserved ejection fraction. This is why the UK authority NICE does not recommend them for patients with preserved ejection fraction.

These days in many cases patients no longer need an appointment for an echocardiogram to discover their ejection fraction, this can now be done on the ward, so beta blockers can be discontinued before discharge after an angioplasty.

ACE Inhibitors or ARBs are routinely given to all MI patients in an attempt to reduce remodelling that occurs as scar tissue forms. Some cardiologists are also sceptical about the long term benefits for patients that are not HFrEF, especially in patients for whom the MI was caused by a narrowing of the circumflex artery.

The trouble is it is hard to question the conventional wisdom, but things are gradually changing, recent research for example has shown what many of us already suspected, that when switching from dual antiplatelet therapy to mono antiplatelet therapy, long term use of Clopidogrel is safer than aspirin, resulting in fewer GI bleeds with the same or better all cause mortality outcomes. So things are changing slowly

Comment Re:Good call (Score 1) 70

The point is simple, if Stellantis shows an inability to get the basic driver assistance features working well, then there is a high probability that they will have failed to build a more advanced system. People like me that has had this poor experience with two Stellantis brand vehicles that are their top of the range latest models will have zero confidence in any autonomous driving capability from the company. Once they can show competence in basic safety features, then I may reconsider.

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