The wear and tear on the body is such that even if you can increase the lifespan to a theoretical 150 years you wouldnt be very healthy for the last 90 or so years. You also need something that adresses the wear on the body. Our hearts arent made for 150 years of use and we build up various plaques and toxins in our bodies as time goes by. Even if we all lived under controlled and ideal circumstances the last seven decades would be pretty much seven decades of being eighty.
Actually, there's some research that strongly suggests that there's only a finite amount of aging going on. What's happening in aging might not be "the body's self repair process falls behind entropy", as commonly thought. Instead, aging would be "the same tradeoffs which favor reproductive success in youth exact a cost later in life"; after some finite time, you've paid those costs in full and aging stops, leaving only a constant risk of disability and death per year instead of the ever-growing one postulated by the "falling behind on entropy" model. In this view, there are still some specific things that actually do wear out with age because they aren't constantly replaced (tooth decay and cornea clouding / cataracts are the obvious ones), but general health doesn't suffer the same fate.
See New Scientist's The end of ageing: Why life begins at 90 (behind a paywall, sadly), which references a demographic study where annual mortality rates became constant above age 93 (Greenwood and Irwin, Human Biology, 1939), a study confirming the same pattern in fruit fly populations (Carey and Curtsinger, Science vol. 258 p. 457 and p. 461, 1992), and an exploration of a mathematical model of mutation which concluded that a mortality plateau is inevitable, not a mere special case (Rose and Mueller; PNAS vol. 93 pp. 15249-15253, 1996). (Of note: Rose is the author of the New Scientist article, with all the confirmation bias that implies.)
Also, the research into aging suggests there are only a handful systemic problems that actually cause it (accumulation of crosslinked proteins; declining telomerase production causing cells to stop dividing; etc.), and if those systemic problems were addressed we could largely arrest the aging process. Aubrey de Gray's TED talk is pretty much mandatory viewing on that front.
It's worth keeping in mind that if metabolism and entropy inevitably led to cell death after 100 years, then human beings as a species would have already died out: sperm and egg cells are metabolically active cells that contain DNA that's millions of years old, and there's no time machine that allows a pristine copy of the germline DNA to be copied forward from conception to adulthood without at least a childhood's worth of accumulated error. Likewise for our mitochondria, pseudo-cells that they are, with their own mtDNA separate from the DNA of the nucleus, exposed to the entropic ravages of the Krebs cycle firsthand without a nuclear membrane to protect it; our bodies pass these pseudo-cells on from mother to child unchanged, without even giving their mtDNA a de-methylation/re-methylation spring cleaning like mammalian nuclear DNA receives. But they thrive in the germ cell line, generation after generation, even as they suffer and decline in the somatic cell lines. There must be a difference in upkeep, some cost that evolution is willing to pay for the germline but unwilling for the somatic lines, that allows the germline mitochondria to remain healthy and "young" for millions of years.