Comment This is pretty big. (Score 4, Informative) 200
This is pretty amazing, although as I write this it remains to be seen if the capsule re-enters correctly. If so, SpaceX will probably combine its next two missions into one. The first upcoming mission is to perform an ISS flyby, followed by a docking. If all goes well with today's mission (and I expect it will!) then the mission in spring 2011 will be an unmanned resupply mission to the ISS.
It's worth noting, though, that the Falcon 9 / Dragon platform is probably not going to be the one taking us to the moon or elsewhere outside of Earth orbit; it was designed to be cheap and fast to develop, which is exactly why SpaceX was able to fly this mission whilst Orion got cancelled. It would take some really heavy modification to even do a lunar flyby.
For now, though, it seems like exactly what we need. If these flights prove to be reliable and inexpensive, then the supply and personnel lines to the ISS are secured, and it'll probably pave the way for Bigelow's space station to launch in a couple years.