Your claims about the fuel reserves of Uranium being thousands of years is clueless because once extraction of Uranium ores falls below 200grams per metric ton of rock Nuclear reactors will no longer generate an energy return on energy invested in the once through cycle used in the reactors in service
The Rossing mine is currently operational at a typical ore grade of 100 ppm, and that's an excavation mine. In situ leach mining (now the dominant form of uranium mining) has much lower energy requirements, making it even more suitable for low grade ores. Some work with bioleaching suggests that mining uranium from phosphates could be practical down to 40 ppm. And the energy requirements for mining uranium from seawater (.003 ppm) could be very low with at-sea processing.
In-Situ leech mining is illegal in the US and Russia, it's primary by-product is radioactive sulfuric acid in the hundreds of megalitre range. In Australia, there has already been an accident involving this in a World heritage National park despite assurances from the mining company that an accident could not happen. Even so, this particular form of mining leaks into water tables, so the concerns for bio-accumulation here is very real as bore water is usually used for farming.
As for seawater extraction even membrane technology has not reached efficiency levels required to get EROEI below 70 petajoules IIRC.
But of course, we aren't going to stay with the reactors we have now for a thousand years, or even a hundred.
Which is where we agree. A full analysis of all the concerns addressed by implementing a proper Nuclear infrastructure is a conversation I have had here many times over the years. Why specific technologies are chosen, which materials technologies are required, what is an appropriate location, how do we address the logistic concerns. Primarily, which reactor technology eliminates Mining, in any form, simultaneously using DU and pu-239 as a fuel whilst eliminating the mass of the waste stream to, unfortunately, something more radioactive with shorter half-lifes and encapsulate fuel reprocessing and reactor disposal.
I think it is possible, unfortunately most of the pro-nukkers here are too short sighted to see past their spite for anyone who questions their social proof to improve the technology to make it viable relative to the energetic potential. Since you are new here, I'll give you the benefit of the doubt and discuss it in another thread some other time.