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Submission + - Superbugs being treated with Brazilian Traditional Medicine (nature.com)

tomhath writes: A recently published study identifies the active compounds in fruits of the Brazilian Peppertree that help heal wounds while also blocking the ability of Staphylococcus aureus and Pseudomonas aeruginosa to necrotize flesh. From the report:

One of the earliest written records concerning the use of S. terebinthifolia date back to 1648 when it was described by Dutch naturalist, Willem Piso, in his book Historia Naturalis Brasiliae... It is included in the Brazilian Pharmacopoeia and has served as a staple in Brazilian traditional medicine for its anti-septic and anti-inflammatory qualities in the treatment of wounds and ulcers as well as for urinary and respiratory infections. Bark extracts have demonstrated antibacterial activity against several pathogens, including S. aureus, Pseudomonas aeruginosa, and Aspergillus species. Bark extracts were also found to be active against Pseudomonas aeruginosa and were effective against peritonitis when injected into the abdominal cavity of rats...

Very little is known, however, regarding the chemistry and bioactivity of the fruits, which were used traditionally as topical poultices for infected wounds and ulcers. Furthermore, while many studies have focused on growth inhibitory, anti-inflammatory, and wound-healing properties of this plant, none have examined its potential as a source of anti-virulence drugs.


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Superbugs being treated with Brazilian Traditional Medicine

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