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Description

Site-Identification by Ligand Competitive Saturation (SILCS) produces three-dimensional maps, known as FragMaps, that illustrate how different chemical functional groups interact with a specific target molecule. By revealing the complexities of molecular dynamics, SILCS offers tools that enhance the optimization of ligand scaffolds through both qualitative and quantitative insights into binding pockets, thereby streamlining the drug design process. This approach employs a range of small molecule probes, each featuring diverse functional groups, alongside explicit solvent modeling and accommodating the flexibility of the target molecule to effectively map protein targets. Furthermore, the technique allows researchers to visualize advantageous interactions with the target macromolecule. With these insights, scientists can strategically design improved ligands with functional groups situated in optimal positions for enhanced efficacy. The innovative nature of SILCS represents a significant advancement in the field of medicinal chemistry.

Description

Scilligence ELN is a unified informatics platform that supports R&D effort across all scientific branches focusing on small molecules, mRNA, ADCs, DEL, and more. Our ELN provides an elegant solution to macromolecule work by leveraging the most advanced HELM implementations. With its purposeful design the Scilligence ELN is a platform that will help your lab elevate internal and external collaborative processes. Benefits • Eliminate data silos by building teams or projects with secure data-sharing • Capture and share data securely in real time • Facilitate data-driven decisions by utilizing machine-readable knowledge base • Generate reports rapidly for publications or patent write ups • Enable quick and efficient deployment with zero client - cloud or on-prem

API Access

Has API

API Access

Has API

Screenshots View All

Screenshots View All

Integrations

Amazon Web Services (AWS)
Elsevier Performance Manager
Microsoft 365

Integrations

Amazon Web Services (AWS)
Elsevier Performance Manager
Microsoft 365

Pricing Details

No price information available.
Free Trial
Free Version

Pricing Details

No price information available.
Free Trial
Free Version

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Vendor Details

Company Name

SilcsBio

Founded

2012

Country

United States

Website

silcsbio.com/software/

Vendor Details

Company Name

Scilligence

Founded

2010

Country

United States

Website

www.scilligence.com/web/scilligence-eln/

Product Features

Product Features

ELN

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