The Guardian reports: A pill taken once a day cuts the risk of dying from lung cancer by half, according to "thrilling" and "unprecedented" results from a decade-long global study. Taking the drug osimertinib after surgery dramatically reduced the risk of patients dying by 51%, results presented at the world's largest cancer conference showed...

Everyone in the trial had a mutation of the EGFR gene, which is found in about a quarter of global lung cancer cases, and accounts for as many as 40% of cases in Asia. An EGFR mutation is more common in women than men, and in people who have never smoked or have been light smokers. Speaking in Chicago, [Dr Roy Herbst, the deputy director of Yale Cancer Center and lead author of the study] said the "thrilling" results added huge weight to earlier findings from the same trial that showed the pill also halves the risk of a recurrence of the disease... Not everyone diagnosed with lung cancer is tested for the EGFR mutation, which needs to change, Herbst said, given the study's findings...

After five years, 88% of patients who took the daily pill after the removal of their tumour were still alive, compared with 78% of patients treated with a placebo. Overall, there was a 51% lower risk of death for those who received osimertinib compared with those who received placebo. The survival benefit "was observed consistently" in an analysis across all study subgroups, including those with stage one, stage two and stage three lung cancer. Chemotherapy had been given to 60% of those in the study, and the survival benefit of osimertinib was seen regardless of whether prior chemotherapy was received.

"It's worth questioning the status quo of technology," argues the Washington Post's Tech Friend newsletter, "including apps as we know them."

Then they tout the benefits of the "non-app app... a hybrid of a website and a conventional app, with features of each" — the unappreciated Progressive Web App (which many still don't know can be installed on your phone's home screen): Web apps look and function pretty much like the conventional apps for your phone or computer, but they clog less space on your device and are less pushy about surveilling you. People who make web apps also say they are easier to create and update than conventional apps... But web apps have been around for years, and most people don't know they exist...

[Traditional apps] come with profound downsides, including Big Tech control, privacy compromises and high development costs. It would be healthy if there were palatable alternative paths to our current app system. Web apps might be part of the solution... At their core, web apps are "the web with an app-like cover," said Rob Kochman, senior product manager for Google's Chrome. Kochman and other web app fans say these apps are less demanding and less intrusive than a conventional app. The web app for Starbucks, for example, takes up just 429 kilobytes of storage on my phone — or less than 1 percent of the storage taken by the standard Starbucks Android app...

And by design, once a conventional app is on your phone, it can access your phone's guts and peek under the hood of your internet network. Web apps are stingier about access, Kochman and other experts told me. "If you're worried about installing some app, you'd probably prefer that as a web app," said a veteran tech executive who helped develop the original technology for web apps. He referred to a web app as "just a website that took all the right vitamins...."

It's difficult to figure out which companies make web apps or find them. There's not an app store for web apps, although there are some attempts like Store.App and Appscope. They're not ideal... Some technologists told me that Apple has held back web apps by limiting their capabilities for Apple devices. The company has said that's not true. And this year, Apple added iPhone feature options for web apps...

We should keep challenging what can feel like immutable parts of digital life, including apps. We have to keep asking: What if there's something better?
It's as easy as "press the three-dot icon, then select 'Add to home screen.'" But it'd be interesting to hear the perspective of Slashdot readers. So share your thoughts and experiences in the comments.

Are you using progressive web apps?

Security guru Bruce Schneier and CS professor Jim Waldo think big tech has underestimated the impact of open source principles on AI research: In February, Meta released its large language model: LLaMA. Unlike OpenAI and its ChatGPT, Meta didn't just give the world a chat window to play with. Instead, it released the code into the open-source community, and shortly thereafter the model itself was leaked. Researchers and programmers immediately started modifying it, improving it, and getting it to do things no one else anticipated. And their results have been immediate, innovative, and an indication of how the future of this technology is going to play out. Training speeds have hugely increased, and the size of the models themselves has shrunk to the point that you can create and run them on a laptop. The world of A.I. research has dramatically changed.

This development hasn't made the same splash as other corporate announcements, but its effects will be much greater. It will wrest power from the large tech corporations, resulting in both much more innovation and a much more challenging regulatory landscape. The large corporations that had controlled these models warn that this free-for-all will lead to potentially dangerous developments, and problematic uses of the open technology have already been documented. But those who are working on the open models counter that a more democratic research environment is better than having this powerful technology controlled by a small number of corporations...

[B]uilding on public models like Meta's LLaMa, the open-source community has innovated in ways that allow results nearly as good as the huge models — but run on home machines with common data sets. What was once the reserve of the resource-rich has become a playground for anyone with curiosity, coding skills, and a good laptop.

Bigger may be better, but the open-source community is showing that smaller is often good enough. This opens the door to more efficient, accessible, and resource-friendly LLMs.
Low-cost customization will foster rapid innovation, the article argues, and "takes control away from large companies like Google and OpenAI." Although this may have one unforeseen consequence...

"Now that the open-source community is remixing LLMs, it's no longer possible to regulate the technology by dictating what research and development can be done; there are simply too many researchers doing too many different things in too many different countries."

Thanks to long-time Slashdot reader mrflash818 for submitting the article

Linux computer vendor System76 shared some news in a recent blog post. "We prefer to disable the Intel Management Engine wherever possible to reduce the amount of closed firmware running on System76 hardware. We've resolved a coreboot bug that allows the Intel ME (Management Engine) to once again be disabled."

Phoronix reports that the move will "benefit their latest Intel Core 13th Gen 'Raptor Lake' wares as well as prior generation devices." Intel ME is disabled for their latest Raptor lake laptops and most older platforms with some exceptions like where having a silicon issue with Tiger Lake. System76 has also added a new firmware setup menu option for enabling/disabling UEFI Secure Boot. The motivation here with making it easier to toggle Secure Boot is for allowing Windows 11 support with SB active while running System76 Open Firmware.

The Washington Post looks at "Americans who want to lower their carbon footprints — but are stymied by their landlords." Homes and apartments burn oil and gas, suck up electricity, and account for about one-fifth of the United States' total greenhouse gas emissions. But current attempts to green America's homes, including billions of dollars in tax credits for energy efficient appliances and retrofits, seem aimed at the affluent owners of detached, single-family homes — in short, Mad-Men-style suburbias. In reality, about one-third of the country's households live in rented apartments or houses... And they generally do not have the spare cash — or the permission from their landlords — to make environmental upgrades. Part of the issue is what's known in economics as the "split-incentive problem," or the "landlord-tenant problem." Roughly 75% of tenants in the United States pay their own utility bills; that means they have a strong incentive to try to conserve electricity, water, or gas to save cash. But their landlords, who have to pay for installing and replacing those appliances and heating systems, don't. They benefit from renting out their properties as quickly and cheaply as possible...

Renters, therefore, are often stuck with leaky housing, inefficient appliances and ancient heating systems. According to one study from 2018, renters use almost 3 percent more energy than homeowners thanks to the split incentive problem... President Biden's signature climate bill includes an estimated $37 billion in tax credits to help households switch to efficient heat pumps, water heaters, or to seal up and insulate their homes. Those credits are applicable to individual homeowners or renters — but not landlords. According to IRS guidance, "the credits are never available for a home that you don't use as a residence." And few renters are going to want to spend thousands of dollars on a heat pump that they'll have to leave behind when they move...

If the landlord problem isn't solved, millions of less wealthy Americans could be left out of the green transition — and will be stuck with higher energy bills. For example, even in the same income bracket, homeowners are almost three times more likely than renters to own electric vehicles — largely because renters lack home charging. There are programs, including some in America's giant climate bill, that could change this... Still, those programs haven't launched yet and aren't expected until at least late this year. And even though renters make up one-third of American households, they're still getting less investment; the tax credits for homeowners are uncapped. The federal government could end up spending well over $50 billion on homeowners, and about $8 billion on renters.

Most renters remain at the mercy of their apartment managers and landlords.

Long-time Slashdot theodp writes: Writing for the masses in It's the End of Computer Programming as We Know It. (And I Feel Fine.), NY Times opinion columnist Farhad Manjoo explains that while A.I. might not spell the end of programming ("the world will still need people with advanced coding skills"), it could mark the beginning of a new kind of programming — "one that doesn't require us to learn code but instead transforms human-language instructions into software."

"Wasn't coding supposed to be one of the can't-miss careers of the digital age?," Manjoo asks. "In the decades since I puttered around with my [ZX] Spectrum, computer programming grew from a nerdy hobby into a vocational near-imperative, the one skill to acquire to survive technological dislocation, no matter how absurd or callous-sounding the advice. Joe Biden told coal miners: Learn to code! Twitter trolls told laid-off journalists: Learn to code! Tim Cook told French kids: Apprenez à programmer! Programming might still be a worthwhile skill to learn, if only as an intellectual exercise, but it would have been silly to think of it as an endeavor insulated from the very automation it was enabling. Over much of the history of computing, coding has been on a path toward increasing simplicity."

In closing, Manjoo notes that A.I. has alleviated one of his worries (one shared by President Obama). "I've tried to introduce my two kids to programming the way my dad did for me, but both found it a snooze. Their disinterest in coding has been one of my disappointments as a father, not to mention a source of anxiety that they could be out of step with the future. (I live in Silicon Valley, where kids seem to learn to code before they learn to read.) But now I'm a bit less worried. By the time they're looking for careers, coding might be as antiquated as my first PC."

Btw, there are lots of comments — 700+ and counting — on Manjoo's column from programming types and others on whether reports of programming's death are greatly exaggerated.

In 2020 Nigeria had the third-most cryptocurrency transactions in the world (behind the U.S. and Russia). But "Nigeria's history with crypto has been a bittersweet one where the citizens have embraced digital assets with open arms but the government remains vehemently against it," writes the site Bitcoinist.

In early 2021 the BBC reported that "In an effort to regulate the market, Nigeria's central bank banned banks from facilitating cryptocurrency-related transactions in 2017, but the ban remained largely unenforced. However, this year the institution doubled down on its stance." In a statement released on 7 February [2021] it cited the need to protect the general public and safeguard the country from potential threats posed by "unknown and unregulated entities" that are "well-suited for conducting many illegal activities". Since then, many Nigerians have reported that their bank accounts have been frozen due to cryptocurrency-related activity...

However many investors with the possibility say they will continue to trade using their overseas bank accounts. They say they can easily revert to peer-to-peer transactions. This means that rather than transferring funds between a financial institution and a cryptocurrency online trading platform, investors transfer funds directly to each other or through a middle person as they buy and sell. This is the method the cryptocurrency community used before the development of the virtual currency marketplace ecosystem in Nigeria...

At the heart of the rise of Bitcoin is a distrust of centralised financial systems and top-down economic control, investors say. Many express their frustrations with government policy and the decline of the Nigerian economy.
This week the Lagos-based Nigerian newspaper The Nation published this explanation of that crackdown from the Central Bank's deputy governor, Kinsley Obiora. "When the central bank started reacting to COVID with what we call printing money and responding to the crisis, a lot of people in the private sector felt that printing of money could lead to hyper-inflation and these private sector people decided to respond by creating cryptocurrencies." Over time, the creators of cryptocurrency, he added, felt that central banks should not be left with the authority to do whatever they like with money. Fearing that such a mindset might cause inflation and reduce the purchasing power of households, the CBN he said responded to what he called "the good aspect of that change because a lot of people actually took to crypto currencies". Fed up with the antics of the cryptocurrency operators, Obiora said the "we kicked them out of our banking system because the opacity of the system is still a threat to financial system stability".

ARM has joined the Linux Foundation's Open Programmable Infrastructure project, "a community-driven initiative focused on creating a standards-based open ecosystem for next-generation architectures and frameworks" based on programmable processor technologies like DPUs (Data Processing Units) and IPUs (Infrastructure Processing Units).

From the Linux Foundation's announcement: Launched in June 2021 under the Linux Foundation, the project is focused on utilizing open software and standards, as well as frameworks and toolkits, to enable the rapid adoption of DPUs. Arm joins other premier members including Dell Technologies, F5, Intel, Keysight Technologies, Marvell, Nvidia, Red Hat, Tencent, and ZTE. These member companies work together to create an ecosystem of blueprints and standards to ensure that compliant DPUs work with any server.

DPUs are used today to accelerate networking, security, and storage tasks. In addition to performance benefits, DPUs help improve data center security by providing physical isolation for running infrastructure tasks. DPUs also help to reduce latency and improve performance for applications that require real-time data processing. As DPUs create a logical split between infrastructure compute and client applications, the manageability of workloads within different development and management teams is streamlined.

"Arm has been contributing to the OPI Project for a while now," said Kris Murphy, Chair of the OPI Project Governing Board and Senior Principal Software Engineer at Red Hat. "Now, as a premier member, we are excited that they're bringing their leadership to the Governing Board and expertise to the technical steering committee and working groups. Their participation will help to ensure that the DPU components are optimized for programmable infrastructure solutions."

"Across network, storage, and security applications, DPUs are already proving the power efficiency and capex benefits of specialized processing technology," said Marc Meunier, director of ecosystem development, Infrastructure Line of Business, Arm and member of OPI Governing Board. "As a premier member of the OPI project, we look forward to contributing our expertise in heterogeneous computing and working with other leaders in the industry to create solution blueprints and standards that pave the way for successful deployments."

"The DPU market offers an opportunity for us to change how infrastructure services can be deployed and managed," Arpit Joshipura, General Manager, Networking, Edge, and IoT, the Linux Foundation. "With collaboration across software and hardware vendors representing silicon devices and the entire DPU software stack, the OPI Project is creating an open ecosystem for next generation data centers, private clouds, and edge deployments."

"The world's most popular online learning course, Harvard University's CS50, is getting a ChatGPT-era makeover," reports Bloomberg: CS50, an introductory course in computer science attended by hundreds of students on-campus and over 40,000 online, plans to use artificial intelligence to grade assignments, teach coding and personalize learning tips, according to its Professor David J. Malan... Even with more than 100 real-life teaching assistants, he said it had become difficult to fully engage with the growing number of students logging in from different time zones and with varying levels of knowledge and experience. "Providing support tailored to students' specific questions has been a challenge at scale, with so many more students online than teachers," said Mr Malan, 46.

His team is now fine-tuning an AI system to mark students' work, and testing a virtual teaching assistant to evaluate and provide feedback on students' programming. The virtual teaching assistant asks rhetorical questions and offers suggestions to help students learn, rather than simply catching errors and fixing coding bugs, he said. Longer term, he expects this to give human teaching assistants more time for in-person or Zoom-based office hours...

Mr Malan said CS50's use of AI could highlight its benefits for education, particularly in improving the quality and access of online learning — an industry that Grand View Research forecasts to grow to $348 billion by 2030, nearly tripling from 2022. "Potentially, AI is just hugely enabling in education," he said.

The Washington Post looks at a new study co-authored by Nels Johnson, senior practice adviser for renewable energy development at the Nature Conservancy nonprofit.

Its underlying point: the current way of building renewables will not work. "If we take the business-as-usual approach, land conflicts will probably prevent us from getting to these ambitious clean energy targets," said Jason Albritton, director of the Nature Conservancy's North American climate mitigation program and one of Johnson's co-authors... In its report, the Nature Conservancy describes two different futures in which the United States achieves net-zero carbon emissions by 2050. In one future — call it "business as usual" — wind and solar farms are built haphazardly, with little consideration for land impacts. In the other future, developers use land more efficiently. Business as usual would require 266,410 square miles — an area around the size of Texas — to fit all the solar panels and wind turbines, plus batteries to store electricity when sunlight and wind are unavailable and long-distance transmission lines to bring power from rural areas to towns and cities.

The researchers used a statistical model to discover the suite of technologies that would minimize land impacts. A smarter strategy, they found, could slash that footprint by more than half, to 114,642 square miles — a little bigger than Arizona. That's still a lot of land, but it would reduce the opportunities for conflict, the researchers said. The model recommends building more solar and less wind, since photovoltaics produce more power with less land than turbines do... The study sees rooftop solar generating far less power than large solar farms. If one in three rooftops have solar panels by 2050 — a high-end assumption — rooftop solar would contribute 15 percent of U.S. solar power, according to the researchers. "It's an important part of the picture, but it will not ever be totally sufficient," Johnson said.

The researchers also found land savings by avoiding productive farmland and instead building on abandoned fields or rehabilitated mines, landfills and hazardous waste sites known as brownfields.

"A little brain stimulation at night appears to help people remember what they learned the previous day," reports NPR — a finding that could one day help people with memory problems, sleeps issues, or depression: A study of 18 people with severe epilepsy found that they scored higher on a memory test if they got deep brain stimulation while they slept, a team reports in the journal Nature Neuroscience.

The stimulation was delivered during non-REM sleep, when the brain is thought to strengthen memories it expects to use in the future. It was designed to synchronize the activity in two brain areas involved in memory consolidation: the hippocampus and the prefrontal cortex.

"Some improved by 10% or 20%, some improved by 80%," depending on the level of synchrony, says Dr. Itzhak Fried, an author of the study and a professor of neurosurgery at the University of California, Los Angeles.

"Amazon employees staged a walkout Wednesday," reports CNBC, "in protest of the company's recent return-to-office mandate, layoffs and its environmental record." Approximately 2,000 employees worldwide walked off the job shortly after 3 p.m. EST, with about 1,000 of those workers gathering outside the Spheres, the massive glass domes that anchor Amazon's Seattle headquarters, according to employee groups behind the effort. Amazon disputed the figure and said about 300 employees participated.

The walkout was organized in part by Amazon Employees for Climate Justice, an influential worker organization that has repeatedly pressed the e-retailer on its climate stance... One employee spoke about how remote work had allowed her to spend more time with her family, while coworkers told her it enabled them to care for newborn children and relatives with special needs. "Today looks like it might be the start of a new chapter in Amazon's history, when tech workers coming out of the pandemic stood up and said we still want a say in this company and the direction of this company," said Eliza Pan, a cofounder of AECJ and a former program manager at Amazon. "We still want a say in the important decisions that affect all of our lives, and tech workers are going to stand up for ourselves, for each other, for our families, the communities where Amazon operates and for life on planet Earth...."

Amazon spokesperson Brad Glasser said in a statement that the company has so far been pleased with the results of its return-to-office push. "There's more energy, collaboration, and connections happening, and we've heard this from lots of employees and the businesses that surround our offices," Glasser added. "

The Red Hat Package Managers for LibreOffice "have recently been orphaned," according to a post by Red Hat manager Matthias Clasen on the "LibreOffice packages" mailing list, "and I thought it would be good to explain the reasons behind this." The Red Hat Display Systems team (the team behind most of Red Hat's desktop efforts) has maintained the LibreOffice packages in Fedora for years as part of our work to support LibreOffice for Red Hat Enterprise Linux. We are adjusting our engineering priorities for RHEL for Workstations and focusing on gaps in Wayland, building out HDR support, building out what's needed for color-sensitive work, and a host of other refinements required by Workstation users. This is work that will improve the workstation experience for Fedora as well as RHEL users, and which, we hope, will be positively received by the entire Linux community.

The tradeoff is that we are pivoting away from work we had been doing on desktop applications and will cease shipping LibreOffice as part of RHEL starting in a future RHEL version. This also limits our ability to maintain it in future versions of Fedora.

We will continue to maintain LibreOffice in currently supported versions of RHEL (RHEL 7, 8 and 9) with needed CVEs and similar for the lifetime of those releases (as published on the Red Hat website). As part of that, the engineers doing that work will contribute some fixes upstream to ensure LibreOffice works better as a Flatpak, which we expect to be the way that most people consume LibreOffice in the long term.

Any community member is of course free to take over maintenance, both for the RPMs [Red Hat Package Managers] in Fedora and the Fedora LibreOffice Flatpak, but be aware that this is a sizable block of packages and dependencies and a significant amount of work to keep up with.
Commenters on LWN.net are now debating its impact.

One pointed out that "You will still find it in GNOME Software, which will install a Flatpak from FlatHub rather than an RPM from the distro."

The Washington Post writes that "Some economists predict artificial intelligence technology like ChatGPT could replace hundreds of millions of jobs, in a cataclysmic reorganization of the workforce mirroring the industrial revolution.

"For some workers, this impact is already here." Those that write marketing and social media content are in the first wave of people being replaced with tools like chatbots, which are seemingly able to produce plausible alternatives to their work.

Experts say that even advanced AI doesn't match the writing skills of a human: It lacks personal voice and style, and it often churns out wrong, nonsensical or biased answers. But for many companies, the cost-cutting is worth a drop in quality. "We're really in a crisis point," said Sarah T. Roberts, an associate professor at University of California in Los Angeles specializing in digital labor. "[AI] is coming for the jobs that were supposed to be automation-proof..."

The technology's ability to churn out human-sounding prose puts highly paid knowledge workers in the crosshairs for replacement, experts said. "In every previous automation threat, the automation was about automating the hard, dirty, repetitive jobs," said Ethan Mollick, an associate professor at the University of Pennsylvania's Wharton School of Business. "This time, the automation threat is aimed squarely at the highest-earning, most creative jobs that ... require the most educational background." In March, Goldman Sachs predicted that 18 percent of work worldwide could be automated by AI, with white-collar workers such as lawyers at more risk than those in trades such as construction or maintenance. "Occupations for which a significant share of workers' time is spent outdoors or performing physical labor cannot be automated by AI," the report said...

Mollick said it's too early to gauge how disruptive AI will be to the workforce. He noted that jobs such as copywriting, document translation and transcription, and paralegal work are particularly at risk, since they have tasks that are easily done by chatbots. High-level legal analysis, creative writing or art may not be as easily replaceable, he said, because humans still outperform AI in those areas.
The article notes that one copywriter lost all 10 of his clients over the last four months — and though one later hired him back, he's now training to be a plumber.

"If you live in San Jose, Dallas, or Vancouver, you may soon be sharing the sidewalk with an army of delivery robots," reports PC Magazine (citing a report from TechCrunch. Uber Eats is expanding its partnership with Serve Robotics to deploy up to 2,000 zero-emission bots: Currently covering Los Angeles and San Francisco, Serve Robotics has been working with more than 200 California restaurants to dish out meals via the Uber Eats platform... Serve's sidewalk robots run seven days a week from 10 a.m. to 9 p.m. They're capable of Level 4 autonomy, allowing them to operate routinely without human intervention, TechCrunch reports.

Uber is no stranger to driverless robots. Together with AI-powered partner Cartken, the firm recently expanded a food delivery pilot from Miami to Fairfax, Virginia, where bots now roam the sidewalks, dropping off meals and providing curbside pickup to locals.
Last week Uber also announced it was making robotaxis available via the Uber app in Phoenix.

TechCrunch argues this new expansion "validates Serve's goal to mass commercialize robotics for autonomous delivery" — while also signalling Uber's deeper commitment to autonomy.