LigPlot+ Description
LigPlot+, a successor to the original LIGPLOT program, allows for automatic generation of 2D interaction diagrams between ligands and proteins. It runs from a simple java interface that allows for easy editing of plots by using mouse click-and drag operations. The program has many major improvements over the previous version, in addition to the new interface. LigPlot+ automatically displays interaction diagrams when two or more ligand protein complexes are sufficiently close. Any conserved interactions will be highlighted. LigPlot+ now includes the updated DIMPLOT program to plot protein-protein and domain-domain interactions. DIMPLOT will generate a diagram showing residue-residue interactions across an interface. Users can select the interface they are interested in. Optionally, residues from one interface can be displayed in sequence to aid in interpretation.
LigPlot+ Alternatives
VeraChem
VeraChem LLC was established in 2000 to advance computer-aided drug discovery. These methods are implemented in high-performance software and provide comprehensive support to users. This is a key strategy of VeraChem LLC for product development. Current VeraChem software capabilities include host-guest and protein-ligand binding affinity prediction, fast calculation and computation of partial atomic charges for druglike compounds, computation and force of energies and forces using all the most commonly used empirical force field, automatic generation and generation of alternate resonance forms for drug-like substances, conformational search using the powerful Tork algorithm and automatic detection and removal of topological and 3D-molecular symmetries. VeraChem's software packages were built from a modular code base.
Learn more
SYNTHIA Retrosynthesis Software
SYNTHIA™ Retrosynthesis software, developed by computer scientists and coded by chemists, allows scientists to quickly and easily navigate novel and innovative pathways for novel and previously published target molecules.
You can quickly and efficiently scan hundreds pathways to identify the best options for your needs.
Discover the most cost-effective route to your target molecule with the latest visualization and filtering features.
You can easily customize the search parameters to eliminate or highlight reactions, reagents, or classes of molecules.
Explore innovative and unique syntheses to build your desired molecule.
Easy to generate a list for starting materials that are commercially available for your synthesis.
ISO/IEC 27001 Information Security Certification will guarantee the confidentiality, integrity and protection of your data.
Learn more
SILCS
Site-Identification by Ligand Competitive Saturation generates 3D maps (FragMaps), showing interaction patterns for chemical functional group with your target molecule. Site-Identification through Ligand Competitive Saturation generates 3D maps, (FragMaps), of interaction patterns for chemical functions groups with your target molecule. SILCS reveals the intricacies and provides tools to optimize ligand scaffolds through qualitative and quantitative binding pocket insights. This allows for faster and more effective drug design. SILCS employs multiple small molecule probes that have different functional groups and explicit solvent modeling to perform protein target mapping. Visualize positive interactions with the target macromolecule. Get insights to design better binding agents with the best functional groups.
Learn more
3decision
3decision®, a cloud-based repository of protein structures, is designed to manage structural data and perform advanced analytics. This allows small molecule and biologicals discovery teams the ability to accelerate structure-based drugs design.
It centralizes, standardizes, and integrates experimental and in silico protein structures derived from public sources such as RCSB PDB, AlphaFoldDB as well as proprietary information, including formats like PDBx/mmCIF, and ModelCIF. This allows for easy access to X-Rays, NMRs, cryo-EMs, and modeled protein structures. It also fosters collaboration and enhances research efforts.
3decision®, beyond storage, enriches entries by adding metadata and sequence data, including annotations of antibodies, binding site details, and protein-ligand interaction. Advanced analytical tools can identify druggable site, assess off-target risk, and enable binding sites comparisons. They transform vast structural data into actionable information.
Cloud-based platform allows for collaboration between research teams.
Learn more
Integrations
No Integrations at this time
Company Details
Company:
EMBL-EBI
Headquarters:
United Kingdom
Website:
www.ebi.ac.uk/thornton-srv/software/LigPlus/
Media
Recommended Products
Secure User Management, Made Simple | Frontegg
Frontegg powers modern businesses with a user management platform that’s fast to deploy and built to scale. Embed SSO, multi-tenancy, and a customer-facing admin portal using robust SDKs and APIs – no complexity required. Designed for the Product-Led Growth era, it simplifies setup, secures your users, and frees your team to innovate. From startups to enterprises, Frontegg delivers enterprise-grade tools at zero cost to start. Kick off today.
Product Details
Platforms
Windows
Mac
Linux
Type of Training
Documentation
Webinars
In Person
Videos
Customer Support
Phone Support
Online
LigPlot+ Features and Options
LigPlot+ User Reviews
Write a Review- Previous
- Next