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Comment Re: AI Coding (Score 1) 116

Strong diasgree on that. I’ve had great results from uploading my schema, uploading a query to optimize (multiple joins, multiple subqueries, etc., that kind of thing), describing the output set I want and letting it come up with a query.

I would actually say I’ve had the _best_ luck with SQL.

Comment Re:"If tastes good, spit it out." - LaLanne (Score 1) 181

Yeah, that's what's worked for me in maintenance. I no longer weigh myself every day but I do at least several times a week. If I get too high, I know to slam on the brakes for a couple of days (at least).

My wife, OTOH, she can't do that. Seeing her weight every day emotionally impacts her, and she eats emotionally.

Comment Re:Yes (Score 1) 181

I couldn't agree more. It's a real struggle to avoid crap at grocery stores. If you stick the produce section and the meat sections, you're in good shape. Once you start hitting the prepared foods, the frozen dinners, the candy aisle, the soda aisle, the chips and crackers aisle, it is really very hard to eat healthily.

Comment Re:Hu? (Score 1) 181

Wikipedia: https://en.wikipedia.org/wiki/Glucagon-like_peptide-1

In the stomach, GLP-1 inhibits gastric emptying, acid secretion and motility, which collectively decrease appetite

NIH https://pmc.ncbi.nlm.nih.gov/articles/PMC4119845/

GLP-1 is of relevance to appetite and weight maintenance because it has actions on the gastrointestinal tract as well as the direct regulation of appetite.

Beyond the scientific facts, if you read anything that people who take these drugs say, you'll find that turning off the "food noise" is perhaps the most central theme. So yeah, GLP-1 drugs do suppress appetite.

Comment Re:"If tastes good, spit it out." - LaLanne (Score 4, Interesting) 181

I'm not arguing against exercise, but with GLP-1 drugs, you literally do not need to exercise to lose weight.

In my late 20s, I lost about 60 lbs of weight, almost entirely through a small number of dietary changes--zero beverages other than water and unsweetened coffee, zero french fries, zero bagged snack foods, zero going out to eat for lunch. I also practiced intermittent fasting, sporadically, for 24 hours. I didn't change my exercising at all.

Now, since I lost the weight, I've taken up more exercise (bike, jog, lift) and I've maintained a steady weight for almost 15 years now.

Bodybuilders say "abs are made in the kitchen, not the gym." They've got a point.

Comment Re:Hu? (Score 2) 181

Cheaper, but not easier.

I'm a "Calories In, Calories out" type guy, but it does seem accurate to say that there is a large percentage of the human population--worldwide--that cannot adapt to modern lifestyle, work types, and food availability. It galls me to say it, but keeping a percentage of the population on appetite suppresants may be the most cost-effective way to control obesity worldwide.

Obesity is skyrocketing around the world. In France, traditionally considered a healthy country, in 2020, 47% of adults have a BMI greater than 25. As of 2014, 24% of French adults have an obese BMI of 30+. (https://www.thelocal.fr/20250527/how-serious-is-frances-obesity-problem / https://www.ameli.fr/paris/assure/sante/themes/surpoids-obesite-adulte/definition-causes-risques / https://en.wikipedia.org/wiki/Obesity_in_France). France today is similar to the United States of maybe 20-30 years ago. Let's hope the trendline changes!

Obesity is surging in India, China, even Africa.

Another factor of obesity, particular in the United States, is that it's strongly correlated with race. Blacks, Hispanics, and Native Americans are all more than twice as likely to be obese as whites, and east Asians have very low obesity rates (though this too is changing). Again, if medicine can help narrow some of the health disparities and improve eating patterns, IMHO, it's probably a good thing.

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