I'm guessing we'll see self driving trucks phase out human drivers gradually by replacing trucks which are due to be replaced anyway. Even if self driving trucks save you the cost of a salary it's still profitable to drive your existing trucks into the ground with human drivers.
When I got my CDL I remember being told you should always have your foot on the break when you go over a hill, but I never remember doing it. There are so many situations where caution is ignored, such as stopping at every railroad crossing, because drivers weigh the risk vs the time investment and decide it's not worth it. An autonomous driving computer however would not value it's time in the same way and should always slow down when extra caution is needed. There is a huge potential to prevent accidents.
Make him NOT a replicant?
How about no.
You mean not a replicant like he he wasn't one in the story the book was based on? Blasphemy.