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Comment: Re: No, they don't work (Score 1) 670

by omnifrog (#45657425) Attached to: Diet Drugs Work: Why Won't Doctors Prescribe Them?

That's totally true. My good friend used to work as a sous chef at a high end (Michelin star) restaurant. One time we were cooking a meal together and he added multiple sticks of butter to things. While I think many of the high end restaurants have moved away from this practice, this is what most of the mid and low end do to make their food taste better and to not use the freshest ingredients. Chinese sauces are the perfect example of this - I might use 1-2 tablespoons of oil (180ish kcal) to stir fry broccoli, but in a restaurant with a sauce, I'd imagine it's far more than that. And yes, on a 2000kcal diet, 180kcal counts, but it's not so bad since everything else in stir fried broccoli is close to free. Bagels are notorious for hiding calories, both their own and what goes in/on them.

However, the massive calories in food is not US specific. Kids in asia eat pure grease from food kiosks everywhere. The french. Most of the girls I know eat a ton and yet are skinny. There are very large differences in how people process calories. The thermodynamics argument was made by Richard Muller at Berkeley and he was rightfully blasted for it. Not because thermodynamics doesn't work, but because you have to draw the system boundary and inputs and outputs correctly before it does work.

Comment: Re: No, they don't work (Score 1) 670

by omnifrog (#45636759) Attached to: Diet Drugs Work: Why Won't Doctors Prescribe Them?

I was the AC above and I did actually read your reply. I agree with your thermodynamics approach, if you'll grant me that the actual equation is:

A*(cal in)-B*(cal out) = C*3500lbs

Where A, B, and C are efficiency factors that depend on physical processes occurring inside the machine that is a person (yep, I'm agreeing with you about the mechanical idea)

When I was training, no I didn't track what I ate very closely. Why would I? I was working out 25 or so hours a week. However there have been times in my life where I tracked my intake obsessively. We can forget the first 10ish lbs, they're easy. But beyond that I seem to lose weight somewhere around 17-1800 kcal/day with an hour of exercise. That's not very much food. A friend decided to try to lose 10 lbs along with me, she weighed 135 and barely worked out. Her baseline food intake was approximately 2500 kcal. 1700 was starvation for her.

And that's pretty much my argument. We can control the height of people with food intake too. If you don't eat enough as a child, you will not be as tall as you would be otherwise, however when someone is very tall or very short we don't blame them for it. Yes, put me in a concentration camp and I'll lose weight. But the question is, why is it so difficult for some people and for others, they just never had to worry about it?

One more interesting data point, in at least 1 followup study for weight loss (I don't have the source right now) formerly fat people had to eat approximately 1/3 less than people who had always been at that weight in order to maintain. That's giant. It's the difference between 3000kcal and 2000kcal. At 2000kcal, you have to be pretty careful about what you eat. At 3000kcal, you really don't need to be careful at all - as long as you aren't eating an entire onion bloom at chili's every day, you probably won't gain weight.

Many people in this comments section keep pointing to one thing or another thing as a pro or a con. But there are a ton of factors, everything from brown fat to gut bacteria, to genetics as well as food availability and type, medication usage, and the overused "glandular (thyroid) problem." (Don't get me started on thyroid problems, they are not very common - genetics is a far easier argument.) And we really can't point to any single factor as THE REASON. However what we can say is that there are a variety of human responses to food, exercise and energy storage and therefore an equation like cal in - cal out = 3500 x lbs may be off in some people by a factor of two. One way to think about this is that auto efficiency has changed dramatically in my lifetime, even though power output has been increasing. It's possible to have two mechanical objects that are very similar in form and function, but that have very different inputs and outputs. And I'm sure you'll agree with me that cars are bound by the laws of thermodynamics.

(There's a study I've looked for in the past and never found, but it's incredibly obvious... I'd like to monitor people's intake and then measure the calorie content of their poo. I'd be willing to bet that skinny people poop out far more calorie rich poo than fat people.)

The Almighty Buck

+ - Bill to require Open Access to Scientific Papers 2

Submitted by
Ponca City, We Love You
Ponca City, We Love You writes "Congress is expected to vote this week on a bill requiring investigators funded by the National Institutes of Health (NIH) to publish research papers only in journals that are made freely available within one year of publication. Until now, repeated efforts to legislate such a mandate have failed under pressure from the well-heeled journal publishing industry and some nonprofit scientific societies whose educational activities are supported by the profits from journals that they publish. Scientists assert that open access will speed innovation by making it easier for them to share and build on each other's findings. The measure is contained in a spending bill that boosts the biomedical agency's effective budget by 3.1%, to $29.8 billion in 2008. The open-access requirement in the bill would apply only during fiscal year 2008; it would need to be renewed in yearly spending bills in the future."
Quickies

+ - Man applies for patent: "Godly Powers"

Submitted by omnifrog
omnifrog (93180) writes "An inventor(?) in Burnsville, MN has filed a patent application for "Godly Powers." Christopher Anthony Roller claims to be a godly entity and then continues to patent the business method of using godly powers for financial gain. Should this patent be granted, it will create a new class of patents and a new patent rush — those dealing with patenting divine intervention."

At work, the authority of a person is inversely proportional to the number of pens that person is carrying.

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