The largest driver for resistance is the over-use of antibiotics in non-health care related fields, like industrial agriculture
There's some truth to that, but to say the "largest" driver is something that nobody has ever demonstrated.
Growing up my family had a hog farm. It was started in the '30s before antibiotics and saw the effect of them on herd health when they became available for agricultural use in the '50s and going forward.
Keep in mind that farms don't use the most expensive antibiotics. Instead, they use common ones such as the various penicillin derivatives and sulfa drugs. They also use antibiotics which were never approved for humans.
So while farms may be the source of resistance to penicillin and sulfa, they can't be the source of resistance to expensive antibiotics used in hospitals. For example, we're running out of TB antibiotics that work. Most of these are never fed to farm animals, so any resistance comes from improper use in the human population. My point is that while farms may be a source of resistance, human misuse must also be a significant factor. Getting rid of factory farms won't solve the issue.
From the experience of my family farm (which was not a factory farm), there's no doubt the improvement with the introduction of antibiotics in herd health was huge. Before antibiotics we had massive die-offs that could take 25% of the herd. The only treatments we had for things such as dysentery were arsenic and copper sulfate, which were very hard on the animals (you basically try to kill the bacteria before you kill the animal). Other diseases such as pneumonia had no treatments. When antibiotics came along in the '50s the improvement was dramatic. While there was some resistance developed to the penicillin drugs, they still were effective in controlling dysentery and other diseases. It did take careful management.
I would be concerned about how accessible my data was without the drivers. So you're using Windows and your data is partly on the platter and partly on the SSD; you reboot to an OS without the driver (i.e. the driver breaks when you upgrade Windows, you boot into Linux, whatever) - can you still get at your data. My guess would be that whilst the contents of the drives will be accessible as two independent drives, they will be in some undocumented format and therefore irrecoverable.
Not necessarily. Don't confuse the decision about *what* to cache with the actual structure of the data on the hybrid drive. Firmware on the hybrid drive can easily keep track of which data on the SSD and HDD is correct, even when you are running Linux or some other OS. The Windows drivers could be used to decide where to put the data (SSD or HDD) during Windows operation, but it also implies that the firmware on the hybrid drive knows where the data is (since it actually put it wherever the Windows drivers commanded).
What about places such as Wyoming and Colorado that are dry (under 50%) for most of the year?
Also, my family had a hog farm growing up. The hogs were outside exposed to the elements. Every November in the early '80s we got hit with a major influenza outbreak in the hogs approaching 100% among the hogs weighing 60 to 180 lbs. There was no major change in the humidity, and didn't depend on rain or other weather events. Assuming the infection mechanism is similar (and certainly the influenza viruses were similar or the same since hogs are the source of many influenza virus mutations crossing over to humans), how does this result explain this?
Sure, it could be always be improved, but look at the actual numbers. You would have to improve it by huge amounts. To reduce nitrogen and phosphorus use you would have to figure out how to recycle it or bioengineer the algae to use much less of it. Recycling it would require a lot more input energy, perhaps making the whole process a net loss no matter what we do. And if we could bioengineer algae to use less fertilizer, we would have done the same thing for our crops a long time ago.
It may be doable, but it won't be for a long, long time. People are already looking at these same issues in our crop production, which is even more important than fuel production. If there was a big win somewhere, we would have found it a long time ago.