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Comment Re:Side Effects (Score 3, Informative) 46

I have a friend with Friedrich's Ataxia, and CRISPR is one of the silver bullets she's praying for. FA cripples then kills you: wheel chair by 25, dead by 40 is often the case (it hardens the heart so it can't pump). While CRISPR has some unknowns and risks, having FA is a certainty. FA affects a single gene pair, so if you can replace either side of that gene, you have solved the problem, the mitochondria will start producing frataxin again, and the nerves will stop being slowly destroyed.

There are no treatments and since it is so rare (1 in 50,000 have it in the US, 1 in 30k in Europe, almost no one in Africa or Asia), few are investing in finding a cure or treatment. FA isn't the only orphan disorder like this. So yes, I'm quite happy to see CRISPR move forward.

Comment Re:No (Score 2) 270

You forgot margin. They have incredible margin on their products. Their concern is total profit, not units sold. They could easily drop their prices in other markets to keep market share, but the net profit to them might be lower. It isn't like iPhones prices are anything relative to their cost. Their price is based on what people will pay.

Comment One unmentioned possibility - ship hardware (Score 2) 234

Besides an NDA and security policy, you can ship them all encrypted laptops. Disable the USB connectors and external data connectors (physically, with epoxy) except maybe a single encrypted keyboard/mouse device like a logitech unified transceiver glued into one port, and only allow vpn into your systems to run executables. Also install gps tracking software in case of loss.

If you have them work on site, that's not cheap. It sounds like you're in the HST business, and that means probably based in NYC, and that means floorspace is a premium. On site work would cost a minimum of $50-100k/yr per contractor.... those contractors would much rather get an extra $45k per year and work from their own office on a $5k super laptop + keyboard + dual monitors, saving you a ton of money per person and making them happy. Have them pay for their own network, and do remote backups every night.

Comment Re: too much $, but no, 3 months pay (Score 1) 186

Bill the city/state? Are you an idiot? The police department doesn't just "fix crime" and send a bill to the tax payers. They ask for more and more funds all the time, so that would get lost.

Whether or no 36k is reasonable or not, the courts can decide. It sounds a little high, but not extraordinarily high.

Comment Re:April fool's day? (Score 1) 168

It really immaterial what the estimates of gifts were. In 2012, the FAA was ordered to have regulations in place by september 2015, to handle commercial UAS. They were explicitly prohibited from regulating hobby drones. UAS tech was blossoming, and the FAA knew this long ago.

In Sept 2015, they updated their AC-91 57, which had to do with hobby UAS. They had been running some tests for commercial flights, handing out occasional section 333 exceptions to movie industries and others.

In Nov 2015, they got feedback that this year's sales were expected to be around 1M+. Fearing what you stated, dumb people flying drones into manned aircraft, they cobbled together a site incredibly quickly requiring registration of all aircraft. They loosely, and wrongly, interpreted the law stating that they may not promulgate restrictions or regulations that affect any hobby or recreational UAS, to read that they may not promulgate rules that affect only hobby or recreational UAS. Despite having 3 years to see this and come up with regulations, they bypassed the mandatory 60 days of public comment stating that it was an emergency situation (caused by their own inaction, which case law has shown cannot be used as an excuse to consider it an emergency).

They are now requiring everyone 13 years old and up to publicly register their names and addresses. In a searchable database, publicly accessible. Failure to do this carries up to a 3 year jail sentence and $25,000 fine. This is the potential penalty for little johnny flying a drone at TWO INCHES above ground level in his own back yard. No joke, the FAA has asserted control from the top of a blade of grass (their words) to the top of the atmosphere. If a neighbor complains about little johnny in his back yard playing with a helicopter that looks like it weights more than 500g, a federal cop has probable cause.

The FAA had orders to have this in place 3 years ago, and failed. Based on that failure, they're claiming an emergency gives them rights to break the law and forgo public comment. The estimates for drone gifts don't matter... the FAA was given 3 years to solve this before it became an issue. Now they are breaking the law that literally requires an act of congress to reverse. (See section 336 which prohibits them from regulating hobby craft.)

There were so many other ways they could have handled this correctly. They could have requested hobby drone manufacturers enclose a copy of AC-91 57 in their packaging. They could have petitioned congress to change the law, allowing some regulation of hobby drones. They could have made a system that didn't allow searching for names and addresses of minors. They could have asked drone manufacturers to, by default, activate geofencing (but not require it). I'm sure there are other even better ways to handle this, too.

Comment Re:April fool's day? (Score 1) 168

The prevailing attitude demonstrated by you is that UAS operators are inherently and collectively reckless. I see that promoted around like the terrorist muslim trope, and that attitude is stupid, unjustified, and ignorant. UAS pilots have been flying longer than manned aircraft pilots. Modelling clubs go back to the turn of the previous century. Like aircraft, there have been some close calls, but UAS operators are far more conscientious than drivers, even commercial drivers, at obeying common sense accepted methods of operation. To my knowledge, over a century of flying and only 2 people have ever been killed from a model aircraft. Compare that to any recreational activity ... go cart racing, boating, fishing, skeet shooting, skiing, etc.

The FAA has previously acknowledged the minimal impact on national air space with only a single advisement circular recommending best practices originally written in 1981, which virtually all fliers read as "obey these suggestions and keep flying". It was recently updated 3 months ago when the FAA was charged with coming up with acceptable regulations for commercial fliers.

It's only because of ignorant knee-jerk statements like yours, with little basis on reality other than anecdotal reports, combined with the FAA's tardiness on creating real regulations that they were given 3 years to create due last september, that the FAA came out with their goofy-ass regulations which violates section 336 of the law explicitly denying them authority to regulate model aircraft.

Comment Re:April fool's day? (Score 1) 168

There are levels to that statement which make it acceptable and unacceptable depending on the circumstances.

A sUAS illegally in the flight path of a manned aircraft should be removed with prejudice. It is extremely dangerous. Let it fall out of the sky. (Unfortunately, it probably won't just drop ... most are programmed to return to sender upon loss of signal. That's where the GPS spoofing would commandeer it.)

A sUAS spotted 6 mi away by this device that is not endangering a manned aircraft (or high security dignitary or something), even if it's where it shouldn't technically be such as a Temporary Flight Restriction, should never be touched. If the operator affects it, it's reckless and should be a jailable offense even if done by law enforcement.

Comment Re:April fool's day? (Score 3, Interesting) 168

Jamming any RF signal is a federal crime, but no they aren't controlled over wifi. But that doesn't matter because intentionally jamming any RF signal is a federal crime.

TFA discussed uses around prisons. That makes sense, and if remote enough, can probably get an exception to jam a signal.

GPS spoofing (also illegal), can interfere with many other issues, most of them life-threatening.

Comment Re:So name them already (Score 1) 265

You are mistaking an actual example (my office) with a stereotype. I didn't say all offices are like mine, I'm saying his stereotype is inherently false and gave a specific example to refute his central claim that the stereotype exists. In the world of Graham's Hierarchy of Disagreement , that would be considered in the top tiers of how to debate a topic, ie: using more than contradiction and instead providing evidence.

Comment Re:The first time didn't help. (Score 1) 265

You would be shocked how often that backfires. They have lawyers on staff, paid to take chicken shit threats and shove them back down your throat. They can outspend you in a second flat, and run you into the poor house defending yourself. No, threatening a company and making claims they intentionally did something bad (particularly when you really don't know the whole story) is just a good way to end up broke and defeated.

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