Blue Origin will eventually have a two-stage rocket that can reach orbit (although they are planning on a much smaller payload than SpaceX for their first iteration). When the booster of that rocket lands without damage, they will duplicate what SpaceX has recently done, although in smaller scale.
Blue Origin to SpaceX at present is a sort of bicycle-to-automobile comparison if you account for the tremendous difference in energy and the application. So, I think there really is an intrinsic difference between the two of them.
If you want to say there's no intrinsic difference, then we need to look at Orbital's Stargazer and Pegasus, which have been carrying small payloads to orbit for years, and there's only been one Stargazer all of that time so there is no question that it's reusable. The only difference is that Stargazer lands horizontally.
We can then look at the B-52 and X-15 combination, in which both stages were reusable, a human was the payload, and we're going back to the late 1950's.