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Corynebacterium glutamicum is an igf-1 elisa kit http://www.cusabio.com/bio1-I-... important industrial strain, widely used in the production of amino acids, organic acids and so on, at the same time, it is also studied aromatics catabolism model system. This study shows that in corynebacterium glutamicum, melting point of benzoic acid metabolic pathways Gentisate coding genes located in the operon genDFM, genR and genKH three closely spaced. The IclR Family the regulatory factors GenR in the 3 — hydroxybenzoic acid and Gentisate, under to increase genDFM and the genKH operon transcription, and also lowered it own coding genes genR of transcription.
Western blot experiments showed that the combination of four loci in the this area, GenR the type of affinity and capacity. The binding sites of the two GenR in the genDFM promoter -35 region and -10 region upstream of the -41 to -81 region, and through them involved in genDFM activated transcription, which belong to the simple activation mode of the I type. The the GenR binding sites R-KHn01 (located between -47 to 16 ) and genKH -35 region of the promoter sequence overlap to participate in the increase of its transcription, which belong to the simple activation mode of a II type.
The regulatory protein GenR combined in the promoter region of its encoding gene genR the R-KHn02 sites, it imprinted region extending from -44 to -67, this the sites involved to cut genR promoter activity. In four GenR binding sites in the existence of a consensus sequence, which is composed of a palindrome structure by site-directed mutagenesis studies found that this structure must be involved in the regulation of GenR. These results indicate that in the participation in the the aromatics Metabolism IclR family, GenR exercise of a new function, which is the first two activation mechanisms exist in the gene encoding a metabolic pathway.
The result of this study provide a new theoretical foundation for a further study of 3-hydroxy benzoic acid and Gentisate metabolic regulation, at the same time, increasing the diversity of the the family of IclR regulation mechanism to study the universal law of this family and their model new basis for melting point of benzoic acid."
The hackers posted the whole NIC.py database containing full names, national ID numbers, street addresses, phone numbers and more. This is not the 1st time that NIC.py, managed by the 2 most respectful Computer Science(CS) Universities of Paraguay, was hacked.
Since the whole BD was released, local white hats could calculate how much money NIC.py was making annually by charging 44 US$ per
The local CS community are urging the NIC.py administrators to do all whats possible to protect the
If they can modify google.com.py, just imagine what they can do to banks and financial institutions. Maybe Google can helps us."
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