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Comment Re:if it doesnt work (Score 1) 464

I was very near sighted all my life, till I lens replacement surgery. Now I can drive without glasses, but have a bit of uncorrected astigmatism, so opted for tri-focals. With my tri-focals I have perfect vision at distance and have the middle lens for the monitor and the speedometer in the car, and the bottom lens makes reading a pleasure! Blended lenses are a compromise for those vanity won't let them admit to anyone they are over 40!!

Comment Re:This raises some questions (Score 1) 172

Had a PRS-505, now have a PRS-T1, never used the Sony store after the original registration. All my content is in epub, pdf, rtf, etc. all acquired from places like and my public library. Get Calibre to use as your ebook library software and it will manage your books on your computer and your Sony PRS-T3. The biggest advantage to the Sony Readers that no one mentions is the ability to sort by more than the title of the books, When you have 500+ books on the Reader, it is nice to be able to sort by series, (which the Sony calls Collections), author and date added as well as just the title.

Comment I've been seeing this a LOT on Facebook (Score 2) 18

I've been seeing this a LOT on Facebook. I myself am not stupid enough to log in to a site I am already logged into, but this has bitten a whole lot of my less savvy "friends"! Seems to be a regular Phishing feature where there is slightly risque picture and when you click to see full size they want you to prove you are over 13 by logging in ! Hah! Not happening!

Comment I remember him for GEM (Score 4, Interesting) 99

The GEM Graphic environment manager, would have been the world standard, well expect for the "Look and Feel" Lawsuit that Apple brought against it when it was released for the IBM PC and Clones. After the settlement it was so neutered as to be fairly useless! It was a dream to use in it's full implementation on the Atari 1040ST. Drag and drop and a windowed environment way before Microsoft got around to it!

Comment The New "Standard" business Model (Score 1) 769

Sell device at or below cost, make sure it only works with your highly, or moderately over priced (ink cart, eBook, razor blade refill, coffee pod, or whatever)!! I this case, I own an espresso machine and can hit the brew button for a second double shot of water for cafe Americano in about the same time as a K-Cup machine! For every day I'll stick to French press and grind my own beans, I own a pump pot carafe, so good to go for the whole day!!

Comment Re:You mean other than what is installed by Defaul (Score 1) 531

That is the expected behavior in Calibre! When you open a file with it, it adds that book to your Calibre Library. If you only want one copy of the book delete the file in the original location. It is after all, primarily an ebook library management system. The conversion feature is really secondary, though very welcome since i don't need an extra application just for that! The editing and creation features have been greatly enhanced lately also! If you care to dig into it, it can do some pretty amazing and complicated things with ebooks, most of which Thankfully I don't need to do!!

Comment You mean other than what is installed by Default? (Score 3, Informative) 531

That would be Thunderbird, followed by Calibre and Skype. I don't care for Evolution, so Thunderbird which is nice and simple to use! Calibre since I have a Sony Reader which uses epub format, since Calibre can convert just about any eBook format to just about any other one, as long as they are not DRMed, it also keeps my eBook library nicely organized. Skype is because one son lives 800 miles away and another 6,157 miles away right now, and Skype works with MS, Apple and Linux OSes so we can keep in touch and see each others faces once in a while!

Comment Have you heard of "Burner" Phones (Score 1) 1

Just for places like that, you make a "Burner" email address. There are many places you can set up a free email account that you can access through your main account, and if it turns out to be a problem, just remove it from the ones you watch and let it fill up and start bouncing stuff back!

Submission + - Melting point of benzoic acid metabolic regulation study for new progress

zdy writes: Recently, new found of melting point of benzoic acid metabolic regulation made progress by the research group of researchers. The studies show ICLR family regulation the protein GenR through two different modes for gentisic metabolic pathway genes genDFM and genKH of expression is activated, further inhibiting the expression of own encoding gene genR. cnsdib vbhx
Corynebacterium glutamicum is an igf-1 elisa kit important industrial strain, widely used in the production of amino acids, organic acids and so on, at the same time, it is also studied aromatics catabolism model system. This study shows that in corynebacterium glutamicum, melting point of benzoic acid metabolic pathways Gentisate coding genes located in the operon genDFM, genR and genKH three closely spaced. The IclR Family the regulatory factors GenR in the 3 — hydroxybenzoic acid and Gentisate, under to increase genDFM and the genKH operon transcription, and also lowered it own coding genes genR of transcription.
Western blot experiments showed that the combination of four loci in the this area, GenR the type of affinity and capacity. The binding sites of the two GenR in the genDFM promoter -35 region and -10 region upstream of the -41 to -81 region, and through them involved in genDFM activated transcription, which belong to the simple activation mode of the I type. The the GenR binding sites R-KHn01 (located between -47 to 16 ) and genKH -35 region of the promoter sequence overlap to participate in the increase of its transcription, which belong to the simple activation mode of a II type.
The regulatory protein GenR combined in the promoter region of its encoding gene genR the R-KHn02 sites, it imprinted region extending from -44 to -67, this the sites involved to cut genR promoter activity. In four GenR binding sites in the existence of a consensus sequence, which is composed of a palindrome structure by site-directed mutagenesis studies found that this structure must be involved in the regulation of GenR. These results indicate that in the participation in the the aromatics Metabolism IclR family, GenR exercise of a new function, which is the first two activation mechanisms exist in the gene encoding a metabolic pathway.
The result of this study provide a new theoretical foundation for a further study of 3-hydroxy benzoic acid and Gentisate metabolic regulation, at the same time, increasing the diversity of the the family of IclR regulation mechanism to study the universal law of this family and their model new basis for melting point of benzoic acid.

Submission + - hacked, redirected

MrJones writes: Last February 20th, hackers supposedly from Iran accessed and modified the database, redirecting to another site.
The hackers posted the whole database containing full names, national ID numbers, street addresses, phone numbers and more. This is not the 1st time that, managed by the 2 most respectful Computer Science(CS) Universities of Paraguay, was hacked.
Since the whole BD was released, local white hats could calculate how much money was making annually by charging 44 US$ per .py domain.
The local CS community are urging the administrators to do all whats possible to protect the .py domain names since the hack was done thanks to a simple RCE vulnerability.
If they can modify, just imagine what they can do to banks and financial institutions. Maybe Google can helps us.

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