Give me a screen that can be mounted, placed, or moved up high so I don't have to bend my neck looking downwards at the screen.
Oh, and the keyboard should be detachable, so it can be placed at the proper height for a keyboard (a few inches below normal desk height).
And a real mouse, also at keyboard level, not desk level.
And the screen should either be portrait, or it should be huge.
I think after I'm done, I'd end up with a desktop.
If you still want portability you should get a docking station for you laptop. then you can plug everything into that for when you need to work.
I've got a wireless KB, Mouse, Monitor, network and audio all connected through mine, and can unplug the laptop by pressing a button.
I don't think that mine can deal with multiple monitors, but it is about 5 years old (and so is the laptop)