If they are not processing the calories, then it is not impacting their blood sugar, glucose or hormonal balances either. You can swallow a balloon filled with sugar, you wont gain weight from it, post dump, and it won't keep your energy up.
yes that was my entire point. how fucking stupid are you? some people will be able to extract more calories from their food, and they will gain more weight. other people will extract less calories, and find it easier to stay thin.
furthermore, some gut bacteria produce lipopolysaccharide, which can increase blood sugar & insulin. this causes the body to try and store more calories as fat, instead of using it for energy or to build muscle. thus lowering metabolism & causing feelings of lethargy, and making exercise less effective at building muscle mass
on the other hand, some gut bacteria strengthen the gut barrier, reducing inflammation & insulin resistance, which leads to lower blood sugar, more available energy, and less tendency for the body to store fat.
I would put up ten grand on a one month inpatient study against your ten grand. The 200+# patient is given 1500 nutritionally balanced calories, a multi vitamin and 2 mandatory sessions a day of 20 minutes on a low impact recumbent bike at 70+% max heart rate average. The patient will be provided with study materials, books, and exercise equipment to occupy the rest of their time. The patient will lose at least 2% of body weight, likely 4%. FYI 8% is max recommended loss rate for that period.
this is a stupid study. of course they will lose weight, but they will be exhausted and hungry and miserable the entire time. you can FORCE people to do lots of things they otherwise wouldn't do themselves. nobody is claiming weight loss is impossible, just that it can be incredibly difficult.