I think that Javascript devs need to learn more about creating a build process to minify and crush the JS dependencies into a single file, rather than which new framework to use for each new project they start.
If your build process takes your dependencies (from npm, for example) and then concatenates them, and minifies them into a single dependency, that saves bandwidth, http calls, and time. If it can do dead code analysis too, to remove those unused functions, then great.
From reading comments, etc, there seems to be an argument into splitting the Ajax convenience methods of jQuery out from the rest, as lots of developers use the former, but you don't need the other niceties such as the highly abstract and overhead inducing $('thing') notation. Perhaps the jQuery 3 work will go some way to fixing this anyway, as it will be far smaller in the non-compat option.