IIRC, there have been experiments at JPL in which bacteria were subjected to ever more Martian-like conditions, and that if the environmental change was slow enough, some bacterial successfully adapted. My brief search didn't turn up those experiments. However...
During the assembly of the Phoenix spacecraft (http://en.wikipedia.org/wiki/Phoenix_(spacecraft)) cultures taken from the clean room in which the spacecraft was assembled and tested noted a shift in the organisms cultured towards those capable of surviving UVC radiation and hydrogen peroxide exposure. The shift towards these extremophiles is notable because Mars has UVC radiation at its surface, and plenty of peroxide species in its soil. The authors of this study speculate that the shift to extremophiles in the clean room was brought about by spacecraft cleaning procedures. Study: "Recurrent Isolation of Extremotolerant Bacteria from the Clean Room Where Phoenix Spacecraft Components Were Assembled", ASTROBIOLOGY
Volume 10, Number 3, 2010, DOI: 10.1089/ast.2009.0396
Abstract: The microbial burden of the Phoenix spacecraft assembly environment was assessed in a systematic manner via several cultivation-based techniques and a suite of NASA-certified, cultivation-independent biomolecule-based detection assays. Extremotolerant bacteria that could potentially survive conditions experienced en route to Mars or on the planet’s surface were isolated with a series of cultivation-based assays that promoted the growth of a variety of organisms, including spore formers, mesophilic heterotrophs, anaerobes, thermophiles, psy- chrophiles, alkaliphiles, and bacteria resistant to UVC radiation and hydrogen peroxide exposure. Samples were collected from the clean room where Phoenix was housed at three different time points, before (1P), during (2P), and after (3P) Phoenix’s presence at the facility. There was a reduction in microbial burden of most bacterial groups, including spore formers, in samples 2P and 3P. Analysis of 262 isolates from the facility demonstrated that there was also a shift in predominant cultivable bacterial populations accompanied by a reduction in diversity during 2P and 3P. It is suggested that this shift was a result of increased cleaning when Phoenix was present in the assembly facility and that certain species, such as Acinetobacter johnsonii and Brevundimonas diminuta, may be better adapted to environmental conditions found during 2P and 3P. In addition, problematic bacteria resistant to multiple extreme conditions, such as Bacillus pumilus, were able to survive these periods of increased cleaning. Key Words: Phoenix—Extremotolerant—Clean room—Spacecraft assembly facility. Astro- biology 10, 325–335.