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Submission + - Uber agrees to temporarily suspend service in Portland (cnn.com) 1

mpicpp writes: Uber is standing down for the next three months in Portland, just one of the cities where it has run into trouble.

The company said it would stop picking up customers there for three months after the city sued, asking a judge to order Uber to stop operating until it is in compliance with safety, health and consumer protection rules.

But Uber fully expects to be back. In fact, this could be good news for Uber fans in the long-run.

The city has agreed to update its laws, creating a new regulatory framework for companies like Uber that tend to fall somewhere between a taxi and a ridesharing service. People use it by requesting a driver with a smartphone app.

Uber, which operates in 60 cities across 21 countries, has run into problems because its drivers do not always meet the city's regulations for taxi and car services.

Last week, for example, a judge in Spain temporarily blocked Uber because the Madrid taxi service said it was unfair to competition and not properly licensed.

Submission + - Scientists Discover That Exercise Changes Your DNA

HughPickens.com writes: The human genome is astonishingly complex and dynamic, with genes constantly turning on or off, depending on what biochemical signals they receive from the body. Scientists have known that certain genes become active or quieter as a result of exercise but they hadn’t understood how those genes knew how to respond to exercise. Now the NYT reports that scientists at the Karolinska Institute in Stockholm have completed a study where they recruited 23 young and healthy men and women, brought them to the lab for a series of physical performance and medical tests, including a muscle biopsy, and then asked them to exercise half of their lower bodies for three months. The volunteers pedaled one-legged at a moderate pace for 45 minutes, four times per week for three months. Then the scientists repeated the muscle biopsies and other tests with each volunteer. Not surprisingly, the volunteers’ exercised leg was more powerful now than the other, showing that the exercise had resulted in physical improvements. But there were also changes within the exercised muscle cells’ DNA. Using technology that analyses 480,000 positions throughout the genome, they could see that new methylation patterns had taken place in 7,000 genes (an individual has 20–25,000 genes).

In a process known as DNA methylation, clusters of atoms, called methyl groups, attach to the outside of a gene like microscopic mollusks and make the gene more or less able to receive and respond to biochemical signals from the body. In the exercised portions of the bodies, many of the methylation changes were on portions of the genome known as enhancers that can amplify the expression of proteins by genes. And gene expression was noticeably increased or changed in thousands of the muscle-cell genes that the researchers studied. Most of the genes in question are known to play a role in energy metabolism, insulin response and inflammation within muscles. In other words, they affect how healthy and fit our muscles — and bodies — become. Many mysteries still remain but the message of the study is unambiguous. “Through endurance training — a lifestyle change that is easily available for most people and doesn’t cost much money,” says Sara Lindholm, “we can induce changes that affect how we use our genes and, through that, get healthier and more functional muscles that ultimately improve our quality of life.”

Comment Re:Neville Chamberlin was not available for commen (Score 2) 230

Germany was spending far more on their military during that time than Britain was. If Britain and France had stepped in earlier, Germany would have been totally unprepared and the war would have ended quickly. Not to mention all of the horrors of the Holocaust that would have been prevented.

If Britain and France had managed to delay the war to "prepare" even more, say a few years, the Luftwaffe would have been dominated by jets, German ballistic missiles would have been longer range and more precise, and they might even have become a nuclear power. I really don't think this is the analogy you're looking for.

Comment Re:We're turning into wimps (Score 4, Insightful) 230

North Korea really hasn't even proven it has a missile that reliably reach Japan. The country is a total basket case run by a violent, completely detached dynasty. It represents a significant regional threat, but if it were to ever do anything truly belligerent, China would yank support and the regime would collapse.

That, to my mind, is the chief threat of North Korea, that when the Kims finally do lose grip, the regime's collapse will be violent for North Koreans and their neighbors.

Comment Re:What are they going to do? (Score 2) 230

Indeed. Of all the groups that make threats against the West, NK seems the one least likely to have the ability or desire to actually attack a Western target. I cannot imagine the fires of hell that would reign down on North Korea should it be demonstrated to be behind mass murders in the United States.

It boggles my mind that anyone seriously believes North Korea is going to start mounting attacks on North American theaters should they screen this film.

Submission + - Woz on being Aussie, and escaping Steve Jobs 'dogma' (afr.com)

Techy77 writes: Apple co-founder Steve Wozniak has become an Aussie permanent resident. Wide-ranging interview on how Apple is escaping Steve Jobs' "dogma", why Google Glass is an admirable failure and why he isn't universally liked within Apple.

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