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Researchers Find Clue to SIDS Early Detection 197

SpaceAdmiral writes "The Globe and Mail is reporting that scientists have found babies who die from Sudden Infant Death Syndrome (SIDS) tend to have an abnormality in their brain stem. By linking SIDS to a biological cause, it may now be possible to test for the abnormality and treat babies at risk of SIDS."
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Researchers Find Clue to SIDS Early Detection

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  • Or... (Score:2, Insightful)

    by Tenareth ( 17013 ) on Wednesday November 01, 2006 @05:03PM (#16679481) Homepage

    They will find out that there are a notable amount of SIDS deaths that are marked as SIDS because doctors didn't want to make the parents feel any worse for putting the kid in a water bed, or with inappropriate bedding... or not sleeping with their kid the first 3 months to help regulate their breathing, or being too far away to have heard the baby cough up some sour milk and drown themselves...

    SIDS is a horrible thing... but quite a few deaths that were actually the fault of the parent for not researching what risk there is to stick a tiny baby in a bed away from them. Heaven forbid we mention that there is a risk associated with anything... there are risks of not breastfeeding, risks of not staying close to the baby, risks of formula, risks of food. Instead of giving parents enough information to make their own decisions (and be liable for them), we don't ever want to infringe on someone's right to be ignorant.

  • by Anonymous Coward on Wednesday November 01, 2006 @05:15PM (#16679711)
    FTA "They studied brain autopsies from 31 infants who died of SIDS in California between 1997 and last year, and compared them to 10 infants who died of other causes"

    One wonders if these 10 were the babies of smokers too, and how many healthy babies they autopsied?

    There don't appear to be enough data points to draw any real conclusions.

    I'd be willing to bet that the correlation to just smoking would be stronger.
  • by AugstWest ( 79042 ) on Wednesday November 01, 2006 @05:23PM (#16679875)
    While this will possibly one day be good news, the number of tests for pregnant mothers and babies is just astounding. It turns into a situation where pregnant women are told "you have a 1 in 4000 chance that your child has X," which creates a lot of worry and concern for what in 3,999 out of 4,000 cases is nothing.

    Frequently, these tests are for things that can't be cured, or that have experimental cures that are sanctioned by the American Societies of Obstetrics/Pediatricians, but the treatment success rate isn't known, nor are the potential harms of a lot of the "cures."

    I'm not belittling the science here, nor am I saying that this isn't a good thing, I'm just pointing out a human cost here -- the stress levels for tests and procedures during these stages of development are very high, and it is an extremely rare doctor who will/can admit that their procedures are experimental.

    If you're pregnant or have a small child, do some research on the tests you'll be given. You'll be amazed at what you discover.
  • by shrubsky ( 661474 ) on Wednesday November 01, 2006 @05:28PM (#16679979)
    After scanning the posts on this topic, I crave a -1 Inhumanly Tasteless moderation option.
  • Nope... (Score:5, Insightful)

    by Junta ( 36770 ) on Wednesday November 01, 2006 @05:36PM (#16680121)
    Natural selection is, in the most basic form, eliminating those traits that do not survive in whatever the current environment is. In this case, assuming that a defect transforms from near certain fatality to usually treatable, even if through human advancement of the 'environment', the environment simply has changed to not weed out that attribute, one way or another.

    Really, if you want to have the heartiest gene pool with respect to the whole natural selection scheme of things, you keep everyone alive you can within reason, even if no apparent benefit can be objectively realized for their apparent defect. The whole deal is that when the environment changes, bizarre things can happen and the more genetic diversity your population has, the more able it is to survive radical changes.

    An example is sickle-cell anemia, most common people with an incomplete grasp of natural selection would think 'that sucks, let nature eliminate that gene from the pool!'. However in the incomplete dominance model it happens to behave, a person heterozygous for sickle cell anemia happens to be much more resistant to malaria.

    In the case of this article, let's assume some neurological pathogen suddenly becomes ubiquitous to the human environment, and somehow the brain stem 'defect' shields those with the trait. Assume this preliminary research is correct and leads to a cure for SIDS, for the sake of discussion. You have a hearty population with a now harmless defect that would be the only survivors. If SIDS wipes out that 'defect' and such a weird pathogen came, the species goes extinct.

    To be trekkie for a moment, a good demonstration is when the TNG crew came upon a planet that eliminated all defective conceptions to not deal with the associated problems. However, their planet was saved from obliteration based on technology in Geordi's visor, which never would have come about in a society where they avoided having to make such a device. The principle is interesting fodder for science fiction, and that I think illustrates well the pitfall of 'let only the best go on'. Best is always relative to the current status quo, which is never unchangeable.
  • by Junta ( 36770 ) on Wednesday November 01, 2006 @05:44PM (#16680311)
    If you understood natural selection, 'diluting' the population is never bad. Genetic diversity to the extent that a species can pull it off always means more flexibility. See my other post around here.

    For example, picture the population genetic diversity represented as a bell curve, with the 'optimum' being the modal value. This curve comes about from a whole set of selection pressures, which in an abstract way in this example maps in the aggregate toward that modal value being allowed to survive.

    If your gene pool is 'more pure', You have a very very steep curve with a very small stardard deviation. Suddenly some aspect of the environment shapes the landscape such that anyone within two standard deviations of that particular curve would die off, leaving a small percentage of population which may or may not be viable, with a high chance of not being viable.

    Now picture a 'dilute' population all over the place with maybe a peak, maybe barely discernible. Now the same calamity comes about and wipes out exactly what would have been two standard deviations of the previously mentioned curve, but now it's only maybe a half of one standard deviation in this, and new curve or curves form to accommodate the calamity from the much more likely viable remaining population.

    This is a really abstract graphical way to complement the physical examples given elsewhere.
  • Comment removed (Score:3, Insightful)

    by account_deleted ( 4530225 ) * on Wednesday November 01, 2006 @05:52PM (#16680465)
    Comment removed based on user account deletion
  • Re:VERY good news (Score:1, Insightful)

    by Anonymous Coward on Wednesday November 01, 2006 @07:25PM (#16681873)
    It probably wouldn't have saved you from the nightmares. You still would have had them, just about something else. Your nightmares weren't the logical endpoint of worrying about SIDS, they were the result of an inborn terror of something bad happening to your kid. It happens to parents, and it happened to me.

    First, I would wake up at night, and have to check to make sure my son was still breathing, or that nothing had happened to him. Waking up so much was killing me. After a month or so, I realized that if he *had* stopped breathing, I wouldn't have woken up for it... and that all of that getting up at night wouldn't do me any good. So, I stopped waking up within a few nights.

    That didn't end it, though... then I would have nightmares of him drowning in the bathtub. So I told myself that wasn't going to happen. The bathroom door was shut, he couldn't get in the bathtub (he couldn't even crawl yet), he couldn't turn on the water, all of that. So the nightmares stopped. Great, right?

    Well, no. Then I still had dreams of other things happening to him, just other things. After going through a few cycles, they waned and went away for good. Listening to all of that, you'd think that I had something wrong with me - but I don't think that I do. Nearly *every single parent* that I know has gone through that to one degree or another. We all know that women have inborn, instinctual behaviors to protect their young, but a lot of people don't realize that men do, to. It goes to the point of a terror of something happening to your child, which makes you become more vigilant, and your kid has a greater chance of survival - succesfully passing along the genes that made you a good protector.

    So again, the test wouldn't have helped. Your brain would have just found something else to worry about. :-)
  • by fuzz6y ( 240555 ) on Wednesday November 01, 2006 @07:48PM (#16682147)
    what is the long term implication for our species' ability to survive?

    Natural selection favors traits that allow a species to survive in its environment, not in some other environment, such as the one its forbears inhabited.

    So, for example, our forefathers were genetically predisposed to not be allergic to peanuts. That was simply not a trait a specimen could express and survive. Nowadays, with effective diagnosis and cortizone shots and "May contain nuts" labels all over the place, it's something you can live with. Nowadays, lots of people are deathly allergic to peanuts, and those people can breed just like everyone else

    Does that mean that the current human species is less fit to survive? Well sure, but only in a habitat substantially different from our own. I kinda doubt we could survive on the ocean floor, either, even though we had ancestors that could. I don't hear any whining about that

    I suppose in some gut reaction kind of way, being reliant on modern technology makes us less "tough" as a species, and that rankles. But does it rankle more than babies dying all over the place? Than having to worry if your baby in particular is going to bite it for what seems like no good reason? I hardly think so.

    It's not like this "damage" is irreversible, either. Genetic drift aside, traits that don't impact fitness in the current environment will vary randomly, so should conditions change due to the science fiction scenario of your choice, the people who have the "right stuff" will survive just fine.

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