I play WoW (no surprise there).
I mostly play a mage. I often find myself in real-world scenarios wishing I could turn people into sheep or teleport myself somewhere. I don't generally find myself wishing I could cast harmful spells on folks in the real world, but I do wish I could cast beneficial spells (buffs) on people, especially intelligence buffs. One of my favorite things I wish I could do is create an aura of clarity that might help people around me avoid stupid mistakes.
Enzymes are things invented by biologists that explain things which otherwise require harder thinking. -- Jerome Lettvin