Re:I get 450 mutations per generation (Score 1)

The summary is misleading. While 12 mutations were found, 8 of those mutations arose in the cell lines that they were using and do not reflect actual mutations between generations. There were only 4 "real" mutations in the ~10 million nucleotides sequenced. If you do the same math with only 4 mutations (so 1200 mutations across the whole genome), then you arrive at 150 mutations per generation, which is what they report (100-200 per generation).