I think they have it right in Mass Effect. It's going to be really really awful and boring. Gunners are going to be mathematicians, and you can turn into some sort of butcher simply by missing.
Gunnery Chief: [as the character enters the Citadel] This, recruits, is a 20-kilo ferris slug, feel the weight. Every five seconds, the main gun of an everest class dreadnought accelerates one to 1.3% of light-speed. It impacts with the force of a 38-kiloton bomb. That is three times the yield of the city-buster dropped on Hiroshima back on Earth. That means- Sir Issac Newton is the deadliest son-of-a-bitch in space. Now! Serviceman Burnside! What is Newton's first law?
Serviceman Burnside: Sir! An object in motion stays in motion, sir!
Gunnery Chief: No credit for partial answers, maggot!
Serviceman Burnside: Sir! Unless acted on by an outside force, sir!
Gunnery Chief: Damn straight! I dare to assume you ignorant jackasses know that space is empty. Once you fire this hunk of metal, it keeps going til it hits something. That can be a ship. Or the planet behind that ship. It might go off into deep space and hit somebody else in ten thousand years. If you pull the trigger on this, you are ruining someones day, somewhere and sometime. That is why you check your targets. That is why you wait for the computer to give you a damn firing solution. That is why, Serviceman Chung, we do not "eyeball it". This is a weapon of mass destruction. You are not a cowboy shooting from the hip!
Serviceman Chung: Sir, yes sir!