My advice, and I haven't graduated. (Score 1)

If it were me I'd make sure, no matter how "high up" the position was, that it was something I found interesting and fufilling. Even if the job is less than challenging, but is part of a field you find interesting and enjoy, I think you will have a better chance of sticking with it. You will, most likely, have the ability to work up to something better (aka more challenging) in that field once you're already there.

What I'm saying is, don't go for a harder job just because its harder. Choose something that you can see yourself doing 5-10 years from now and begin where you have to.

Of course, I've yet to even graduate with my B.S. in computer science :)