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Games

The State of WiiWare, Xbox Alternatives 73

CVG is running a piece discussing the current state of WiiWare, and where they expect it to go in the future. They point to the success of Mega Man 9 on WiiWare and other platforms, but worry that the perception will arise that certain games are "too good" to be featured on WiiWare. GameSetWatch has a related interview with independent developer Ninjabee discussing their recent games and comparing WiiWare with Xbox Live Arcade. Meanwhile, Microsoft has announced that the new Xbox Experience coming in November will included their Community Games initiative, which will allow amateur game developers to create and share games using the XNA development tools.
Medicine

Why Most Published Research Findings Are False 259

Hugh Pickens writes "Researchers have found that the winner's curse may apply to the publication of scientific papers and that incorrect findings are more likely to end up in print than correct findings. Dr John Ioannidis bases his argument about incorrect research partly on a study of 49 papers on the effectiveness of medical interventions published in leading journals that had been cited by more than 1,000 other scientists, and his finding that, within only a few years, almost a third of the papers had been refuted by other studies. Ioannidis argues that scientific research is so difficult — the sample sizes must be big and the analysis rigorous — that most research may end up being wrong, and the 'hotter' the field, the greater the competition is, and the more likely that published research in top journals could be wrong. Another study earlier this year found that among the studies submitted to the FDA about the effectiveness of antidepressants, almost all of those with positive results were published, whereas very few of those with negative results saw print, although negative results are potentially just as informative as positive (if less exciting)."

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