It works for us! (Score 1)

At a local computer store I work at, our tech cd's have batch files that install, update, and run scans with these programs. We also have other programs we run such as hijack this, and some program specifics like About Buster or others to get the real nasty ones. After we do the cleanup, we don't see many of the same customers back for spyware problems by telling them to run spyware scans regularly. I usually install Microsoft AntiSpyware as well if I'm not feelin too lazy. Also don't forget to clean out temporary internet files and other temp folders after cleaning, otherwise you will likely some if it back very soon.