Is this a serious question? There isn't even agreement on what the 10 commandments *are*: http://en.wikipedia.org/wiki/T...

How about the airport? It's remarkably easy and convenient to print at a kiosk there!

Environmentally-induced mutation definitely does play a large role in tumor formation--that's why smoker's get lung cancer, sunburns can lead to skin cancer, etc! There's also viruses that can play a role.

However, we also don't really know how many mutations are necessary for cancer to arise, and one of the first things to happen may be either immortalization through mechanisms including telomerase activity (or the tumor could arise in stem cells where this activity is already present) or (more often) a mutation that in turns leads to an increased mutation rate! Regardless, it's probably not that many mutations, and don't underestimate just how large a number of cells there are in the body (on the order of 10^13 - 10^14)!

Where did you get your numbers? Human DNA replication (in normal cells with no damage) is 99.99999999% accurate (i.e. about 1 mutation per 10^-10 base pairs). Please do not mod parent informative for this misinformative post!

Sure...but on the other hand, as soon as you start typing "Gy" into imdb, Gyllenhaal comes up complete with a photo and a big-name movie (for both Jake and Maggie). And if you type in secretary, it brings up an option to go straight to the movie page--without even having to type Gyllenhaal too. So I'd say that's quite a win for imdb. You don't need to know who is in the movie, you don't need to be able to spell "Gyllenhaal"....

To clarify, you want each of your markers to carry maximum information. SNPs are the easiest/cheapest markers to genotype, and represent positions in the genome where some chromosomes in the population have one nucleotide (e.g. G, one of the alleles) and others have a different nucleotide (e.g. T, the other allele). (I say chromosomes instead of people, since people are diploid and will have 2 copies of each chromosome. Diploid genotypes are then GG, GT, or TT for a G/T SNP). To maximize information, you want to choose a SNP where the probability of these genotypes is relatively even--maximized if the proportion of G's and T's in the population are equal, leading to 25% GG, 50% GT, and 25% TT.

While the parent is correct that 24 SNPs is sufficient in a given population, in practice it's probably hard to choose 24 SNPs that cover ALL populations in the world well (since a SNP with a high minor allele frequency in, say, Europeans, may not have a high minor allele frequency in Asians, or Indians, or Australians...