The typing experience is superb! Although the layout is slightly different from the classic 104 key standard, I found I was able to touch type from day one, including cursor keys, I am also able to type faster and with less fatigue. I often prop up the front edge on a wrist rest to gain a reverse tilt, which helps with wrist strain.
Although Logitech discontinued this model (I bought two for $20 at that time), they now offer two illuminated models with the same PerfectStroke key mechanism - one wired, one wireless, and both overpriced. I'm keeping an eye on DealNews to grab one when they briefly hit a reasonable price point.
C'est magnifique, mais ce n'est pas l'Informatique. -- Bosquet [on seeing the IBM 4341]