Comment SpeechVibe (Score 1) 175
Try SpeechVibe... It works well with dictation, is the best solution for command-and-control (you can navigate through the menus and dialog items with it), and can even paint stuff through tougher operations like drag and drop, etc...
It is for Vista. As far as getting it to work on OS X, you will have to investigate to have a virtualization system on OS X.