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Comment Compression by Reference (Score 1) 138

The sequence read archives (such as the one hosted by NCBI) as a repository for this sequencing data, uses "compression by reference," a highly-efficient way to compress and store a lot of the data. The raw data that comes off these sequencers is often >99% homologous to the reference genome (such as human, etc), so the most efficient way to compress and store this data is only to record what is different between the sequence output and the reference genome.

Comment Look at the dosing! (Score 5, Insightful) 252

The experiments in mice were performed at 12.5mg/kg, which would be (for the average 65-kg human) a shocking 812.5mg of Triclosan. If your standard amount of handsoap and toothpaste is 2ml that's like brushing your teeth with a 1/3 solution of triclosan and swallowing it.

Like most of the research in PNAS this was not subjected to the high level of peer review expected in most scholarly journals and this paper got through without regard to its relevance and real-world significance.

At a high enough dose, caffeine causes cancer in lab animals. But not at the doses even Slashdotters consume.

Comment Re:Growth (Score 1) 138

While your statement is correct the cancer risk is minimal.

A typical xray is about 1-10 mrem. You get about 5 mrem of radiation dose from just an airplane ride. If a child lives in a concrete apartment building he/she will receive 100 mrem just from the radiation the concrete gives off. Annual occupational exposure limits for radiation workers are 5000 mrem. A deadly dose of radiation is about 50,000 mrem.

Comment Go to the cloud (Score 1) 239

For individual research units, the cost of maintaining the processing power and storage space for these types of projects can be cost-prohibitive. Cloud-based options offer distributed computing power and low-cost storage that is often a more economical solution that paying for the equipment in house, especially when genomic projects can come in spurts rather than a continuous stream.

Disclaimer: I work with large amounts of genomic data and use both in-house and cloud-based analysis tools.

Education

BYU Prof. Says University Classrooms Will Be "Irrelevant" By 2020 469

dragoncortez writes "According to this Deseret News article, University classrooms will be obsolete by 2020. BYU professor David Wiley envisions a world where students listen to lectures on iPods, and those lectures are also available online to everyone anywhere for free. Course materials are shared between universities, science labs are virtual, and digital textbooks are free. He says, 'Higher education doesn't reflect the life that students are living ... today's colleges are typically tethered, isolated, generic, and closed.' In the world according to Wiley, universities would still make money, because they have a marketable commodity: to get college credits and a diploma, you'd have to be a paying customer. Wiley helped start Flat World Knowledge, which creates peer-reviewed textbooks that can be downloaded for free, or bought as paperbacks for $30."

Comment Version 2009 (Score 1) 693

Just call it what it is -- the internal version can be 1.0.0.3 or whatever, but the version on the box and in all literature can be Version 2009 (or the year of release). That was popular about 8 years ago...and still works too!

Data Storage

Tips For Taking Your Laptop Into and Out of the US? 940

casualsax3 writes "I'm going to be taking a week long round trip from NYC to Puerto Vallarta Mexico sometime next month, and I was planning on taking my laptop with me. I'll probably want to rip a few movies and albums to the drive in order to keep busy on the flight. More important though, is that I'm also going to be taking pictures while I'm there, and storing them on the laptop. With everything in the news, I'm concerned that I'll have to show someone around the internals of my laptop coming back into the US. The pictures are potentially what upsets me the most, as I feel it's an incredible violation of my privacy. Do I actually need to worry about this? If so, should I go about hiding everything? I've heard good things about Truecrypt. Is it worth looking into or am I being overly paranoid?"

Leaving Early May Cost You Time 678

markmcb writes "OmniNerd has an interesting traffic article demonstrating how leaving early for work may cost you time. Brandon Hansen uses a year's worth of data collected on his urban drive to and from work along with statistical analysis to show the effects of varying departure times and considering external factors like nearby school districts' schedules. In the end, a minor shift in his departure time results in saving driving hours equivalent to over a third of the vacation time given annually by his employer."

PA Seizes Newspaper's Computers 314

twitter writes "Computer equipment from the Lancaster Intelligencer Journal was seized for alleged improper data access and disclosure. From the article: 'If the reporters used the Web site without authorization, officials say, they may have committed a crime.' Journalist are understandably upset that confidential information, that has nothing to do with the investigation, will be found and used for retribution."

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