So much history (and transition of Apple as a company) involved in Lisa...
68k with custom memory map, two very funky disk interfaces (twiggy and pippin), big bitmapped display (rectangular, not square like the Macintosh)
As much as possible written in Pascal, designed and documented!
I'll call it the first large scale Apple project designed and built by engineers, particularly software engineers (the design part is important)
Yes, Apple /// SOS was designed and built by software professionals (Tom Root, Bob Etheredge, and many more), but not at all the scope of Lisa which went from the core OS out to the document model
Such incredible effort went into Lisa -- the origins of Quickdraw graphics (Atkinson), modeless text editing (Tesler), software design on a large scale, a document model rather than an app-centric model
Of course some issues (problems), such as applications software tied to the serial number of the machine, not enough RAM, not enough disk space, not enough CPU horsepower
And even though many of the foundations for the Macintosh came from Lisa (mouse, bitmapped screen, Quickdraw, overall engineering rigor), with very few exceptions, if you worked on Lisa, Steve considered you to be second rate (a view not shared by most of engineering)
Lisa also lead the way in other ways -- the locked-down, invitation only secrecy and internal isolation that was anathema to the Apple ][ and Apple /// worlds of that time, but which has come to define the current Apple.
Lisa was an amazing development, particularly at that time in Apple's history. I have so much respect for those people, and for the Apple /// team as well. At the time, the biggest knock both these projects took was not matching the (incredible for the time) sales volume of the Apple ][.
I saw this happen from across the street in Bandley 3... An incredible time at Apple, and in the computer racket.
(Apple Employee 1xxx)