For most gaming applications ATI ran away with this round in the price/performance category. For F@H though, I think this is going to be a very interesting card, Nvidia just folds better than ATI. There are numerous reasons for this, and finger-pointing is futile, but thats the cold hard fact. The extended time that software-side engineers have had to play around with CUDA seems to have been beneficial. In time, and with work on their OpenCL implementation, I think the current generation Radeons will catch up, but not for a while. I'm mostly interested in seeing how this card performs against the GTX 295, currently the best single PCB GPU folder. If the retail prices of the GTX 470, with its optimized CUDA Cores, stays within the $350-$400 range I'd love to pick one up to play with.
Do not take this as an endorsement for either company. I simply choose the best hardware to fit my specific needs: ATI for gaming, Nvidia for F@H