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Comment No evidence HCQ or CQ works for COVID-19 (Score 5, Informative) 151

The trials that support HCQ's use in COVID-19 are small and have many methodological flaws. People out there would like to believe that there is some sort of treatment for SARS-CoV-2 but the simple answer is that currently nothing out there works, and that there has rarely ever been a pre-existing medication with significant antiviral properties against a new emerging virus. This review of Gautret et al.'s work raises a lot of questions about its scientific vigour: https://scienceintegritydigest... This paper suggests that HCQ prolongs viral shedding (but not in a statistically significant way. Also at least this study was randomised): http://www.zjujournals.com/med... But who knows, there's worse things to die of that torsades and optic neuritis.

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