Give PointSec a try (Score 1)

I had such experience of making choice between FDE solutions half a year ago. TrueCrypt 5 had sucked on several Dell laptops. Vista just didn't boot normally, safe mode only. We stopped at PointSec, it's deployed very easily and performs perfect AD integration. But if you are planning to rovide PGP messaging services at the same time, then maybe PGP Desktop would be the better choice. Good luck!