Meh, I prefer a gamepad.
I feel that mouse/keyboard is a hack that only works for certain types of games. Games aren't meant to be played with mouse/keyboard, it just happens to be what everyone had laying around. It's also less comfortable.
I can understand certain types of games converging to a mouse-like control. However the keyboard is a joke for gaming. At least drop the keyboard and give me a real gaming tool for my left hand.