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Comment Re:Unfortunately no and I have a reason (Score 3, Informative) 379

I constantly switch between the major C languages (not a major feat), C, C++, Java, C# and my resume has Visual Basic, Ada, Python, Perl, Assembly, FORTRAN, Lab Windows

A lot of these languages are kind of samey-samey; the mind expansion he's talking about comes from working in languages that use very different programming models that make you approach problem-solving in new ways. Try adding, say, Haskell (or SML or ELM), Forth, and Prolog to the list, for starters.

Comment Re:Asking? (Score 1) 198

It does not. People elsewhere in the thread have confirmed this, as does Consumer Reports:

http://www.consumerreports.org...
In most states, to get the low-cost, EpiPen alternative, you can't use a prescription for "EpiPen" from your doctor. That's because pharmacists at your drugstore likely won't be able to automatically substitute the low-cost version if your prescription is written for EpiPen. Instead, ask your doctor to write a prescription for an "epinephrine auto-injector"

Comment Re:Asking? (Score 1) 198

I've never had to ask a doctor to prescribe a generic EVER. If there is a generic it just gets substituted by the pharmacist because that's how things actually work. If there is a generic, you don't really have to do anything.

Whether or not the pharmacist is allowed or required to substitute a generic varies by state (e.g. it's mandatory in NJ and unlawful in OK, and up to the policy of the pharmacy in FL; and in states like HI/KY/NC/SC/TN the legality varies by drug).

It also varies from case to case (in this case, while both are epinephrine pens they aren't AB substitutable according to the FDA, so even states that allow some substitution for brand-name medications wouldn't allow it here)

There's literally no reason for a doctor to prescribe by brand name unless they believe it's one of the few cases where a particular brand is actually more effective: If the doctor prescribes the generic drug name, then it doesn't matter where you get it filled. You can get whatever brand is cheapest. If the doctor prescribes by brand name, then you're at the mercy of the local laws and regulations of the place that you fill it as to whether you can substitute or not.

Comment Re:Isn't earning a profit part of capitalism? (Score 1) 198

Patents are enforced to protect innovation in research, not to protect price gouging on a generic drug in a particular form factor. Capitalism in concept is about minimizing the lost value from unmet demand and wasted supply (not everything can be salvaged). Additions onto that are political and ideological not practical. In fact the actions of Mylan are opposed to capitalism as they are setting overly high prices on a captive market (Medicaid recipients)

1. Medicare, not Medicaid
2. Why is Medicare a captive market? Why don't they just buy one of the cheaper alternative ephinephrine autoinjectors (like Adrenaclick) instead of EpiPen?

Comment Re:It's not innovative (Score 4, Informative) 198

That list of problems with competitors fails to mention Impax's Adrenaclick, which has been FDA approved and sold in the US market freely since 2010; it's widely available (it's sold at Rite Aid, Walgreens, CVS, Walmart, Target, etc) and much cheaper than EpiPen.

Comment Re:feds should go after themselves (Score 2) 198

The fact that Mylan can charge these prices is government regulations and government-granted monopolies.

It's more dumb consumers and good marketing. There are cheaper alternatives like Adrenaclick available if you ask for a generic epinephrine auto-injector rather asking for Epipen by brand-name. See, e.g, Consumer Reports http://www.consumerreports.org...

Meanwhile, if you’re looking for a low-cost alternative to the EpiPen, we recently recommended generic Adrenaclick, also referred to as an "epinephrine auto-injector."...In most states, to get the low-cost, EpiPen alternative, you can't use a prescription for "EpiPen" from your doctor. That's because pharmacists at your drugstore likely won't be able to automatically substitute the low-cost version if your prescription is written for EpiPen. Instead, ask your doctor to write a prescription for an "epinephrine auto-injector" or "generic Adrenaclick."

Comment Re:Was Already Approved For "Generic" Tier Rebates (Score 2) 198

And if that's true - that Medicare was already applying the âoenon-innovator multiple sourceâ rebate schedule to the EpiPen back in 2007 - then that makes this case a lot murkier. The Feds would then have to make a case as to why the drug can and should be reclassified at the higher âoesingle sourceâ tier. It's clear that in practice the EpiPen is a single source device

Is it clear? There are other options out there (e.g. Adrenaclick), if you get your doctor to prescribe an "epinephrine autoinjector" instead of specifying "Epipen" by brand name. How different is that from other drugs? If you get a prescription for, say, Lipitor, can you fill that with a generic? Or can you only do that if you get a prescription for atorvastatin rather than the brand-name?

http://www.consumerreports.org...

Comment Re:Simple Solution (Score 4, Informative) 198

The drug, epinephrine, is generic. It is adrenaline, which your body produces naturally. There is no patent stopping generic injectors, but so far none have been approved by the FDA.

Yes, they have. Adrenaclick's been on the market (with FDA approval) for 5+ years, and costs like 1/4 what Epipen does.

http://www.consumerreports.org...

Comment There are several projects out there (Score 5, Informative) 186

Not yet mentioned yet is http://lucida.ai/ -- it's the successor to Sirius, and where all the ongoing development is focused.

Major options that are mentioned elsewhere in the thread:
https://mycroft.ai/ (One of the most advanced,can actually be used in a pretty useful manner now, but sends snippets to Google for voice recognition--they intend to change that eventually, and they don't have a full-time open mic. Plus they aggregate audio across users so it's less identifiable as from a single source).
https://wiki.mozilla.org/Vaani (from the Mozilla project; supposed to enter beta this month according to that page)

Comment Re:What do you want us to do? (Score 4, Informative) 537

Not that guy, but one company which springs to mind immediately is HGSI. They cured AIDS, were bought out by Glaxo-Kline-Smith and all their research was shelved because GKS has a treatment-for-life product which a cure would have made obsolete.

Yeah, except that's not true at all. HGSI had a ccr5 monoclonal antibody in clinical trials, but it hadn't shown itself to be as effective as other existing medications let alone constituting having "cured AIDS". And Glaxo has been working on ccr5 agonists of their own (e.g aplavoric), with similarly mixed results.

There's a ton of money and prestige in an AIDS cure, there's no way a pharmaceutical company would submarine it.

And Glaxo and HGSI were beaten to the punch on CCR5 agonists by Pfizer, who got FDA approval for maraviroc (brand: Selzentry) and are making millions off of it.

Comment Re:State Endorsement of Religion (Score 2) 271

Sure seems to me that a special exemption for one particular work of fiction is a clear violation of separation of church and state.

There's no Bible exemption in the law. It does exempt purchases made by religious organizations (as well as charities, accredited educational institutions, and volunteer firefighting organizations), but there's no preference for a particular religion or for religious nonprofits over, say, the Red Cross, Greenpeace, or Planned Parenthood.

Comment Re:Only the Bible? (Score 1) 271

There is no Bible exemption. There's an exemption for purchases by religious organizations (and charities, accredited educational institutions, and volunteer firefighting organizations), which doesn't explicitly mention one religion over another or prefer a religious organization over the Red Cross, Planned Parenthood, or UNICEF.

Comment Re:WTF PA? (Score 5, Informative) 271

Glad to see the separation of church and state is alive in well in the U S of A!!!
"...digital versions of the Bible will be exempt from the digital downloads tax"

If they wanted an exemption that would do society some good, they should exempt textbooks, but then kids might get exposed to more of that heretical "science."

The summary is terrible.

Textbooks purchased from or through accredited schools are exempted. The Bible is not specifically exempted, but purchases by qualified charitable organizations, volunteer fire companies, religious organizations and nonprofit educational institutions are unless used in an unrelated business capacity--there's no particular preference for religious organizations over other social nonprofits, and nothing singling out particular religions.

The tax is not specifically on streaming video. It extends the state's 6% sales tax to online purchases--streaming video is included, as are video downloads, streaming and downloaded audio, and other online purchases like ebooks, apps, games, e-greeting cards, etc.

Comment Re:Be accountable (Score 1) 139

https://en.wikipedia.org/wiki/...

In the Men's Singles tournament first round, the American 23rd seed John Isner defeated the French qualifier Nicolas Mahut after 11 hours, 5 minutes of play over three days, with a final score of 6–4, 3–6, 6–7(7–9), 7–6(7–3), 70–68 for a total of 183 games.

They had it called due to night the first day, then again on the second day after playing all day, and finished on a third day.

The next year at Wimbledon they met again in the first round. Isner won handily in straight sets, 7-6, 6-2, 7-6.

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