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Comment Re:LDAP and Linux are freely licensed (Score 3, Interesting) 68

I don't think the main issue is the end-user software. It's all the other stuff that makes the company work. I work for a small startup, and I can list at least a dozen software platforms that we use, and I'm sure there are dozens more; none of which we could trivially migrate away from. (Fortunately, most of which I don't really want to, as they work fairly well.)

Besides the technical stuff, there's the HR benefits, the expense reporting, the door lock manager, the office reservation system, etc. I'm sure all of these are subscriptions. Many are probably quite inexpensive, but some aren't.

At some point, it will be cheaper to tell Claude, "We use the OverPriced platform. Examine our usage of it, and develop a replacement platform tailored to our needs, and include a transition plan to suck all our existing data and configurations over to the new system." But then there's one more system to support locally, which may not be worth the cost. Or if OverPriced is too ridiculous, do the same, but spin it off as FairPriced and compete.

Comment This is the treatment you are looking for (Score 1) 33

While they're currently only applying this to people with extreme cholesterol problems, there's no reason the same treatment wouldn't work for anyone on statins. They use different dosages to impact a different percentage of the liver cells to adjust cholesterol levels, essentially introducing a mutation found in a small percentage of the population where a particular gene is inactive. For people with more manageable cholesterol levels, they would presumably just need a lower dosage to get levels below that where medication is required.

So for now, this will likely be only used in extreme cases, but over time, this could be an alternative to statins just like lasik is an alternative to glasses.

I would love to stop taking my statins, and I'm sure many other people would also opt for something like this. Once they get more experience in the more extreme cases, there's every reason to believe they'll open it up for wider usage. Apparently between 50% and 65% of people fail to take their statins consistently for various reasons, so this could be much more effective and reducing heart disease.

Comment Re:What could possibly go wrong?!?! (Score 2) 33

They're effectively introducing a rare genetic mutation. They found some people who have extremely low cholesterol, and it's due to one broken gene, so they introduce that change in some percentage of the liver cells to reduce the cholesterol levels. They can do studies of people who already have the mutation naturally to get an idea of any expected health impacts.

Comment Lidar is nice, not required (Score 2) 219

I think the Rivian approach is the best. They're basically copying the Tesla model of having their fleet send the sensor recordings back and then using them as training data. While they're far behind right now, they'll catch up quickly, as they can copy a lot of the basic technology that's now established instead of having to invent everything from scratch and make wrong decisions along the way. The difference is Rivian is including lidar, so they just include the matched video and lidar recordings as a larger training data set. I'm convinced that if the price of lidar was more like it is today back when Tesla started selling FSD in 2016, then that's exactly what Tesla would have done, but Tesla is now stuck with their solution with ten million cars already on the road.

But in clear weather conditions, I don't think lidar really helps that much. Most human accidents would be avoided if drivers had better situational awareness and didn't have gaps in paying attention, and the cameras solve that.

Comment Defy FUD, Meet Expectations (Score 5, Insightful) 110

I don't know what expectations these are defying unless they're from those created by anti-EV FUD. I thought it was pretty clear that EV batteries usually last longer than the cars themselves. If 250K is exceeding expectations, then the expectations are wrong and haven't been supported by the data for a long time.

Comment Self-Hosting (Vaultwarden) (Score 1) 70

I love that I can self-host Bitwarden, and I do it with Vaultwarden, which is open source, so I have no fear of it going away. But if the company got really obnoxious and blocked self-hosted servers from the browser plugins, then I would be in big trouble. I don't think the changes listed suggest that they're going to do that anytime soon, but it's something I want to keep an eye out for.

Comment Meanwhile, at Carnegie Mellon... (Score 4, Interesting) 193

Jensen Huang to college grads: "Run. Don't walk" toward AI

https://www.axios.com/2026/05/...

Nvidia founder and CEO Jensen Huang told graduates at Carnegie Mellon University in Pittsburgh yesterday that demand for AI infrastructure is creating a "once-in-a-generation opportunity to reindustrialize America and restore the nation's capacity to build."

Why it matters: With many college grads fearing AI could obliterate their career dreams, Huang pointed to boundless opportunity as a "new industry is being born. A new era of science and discovery is beginning ... I cannot imagine a more exciting time to begin your life's work."

Nvidia, which makes AI chips, is the world's most valuable company. Huang told 5,800 recipients of undergraduate and graduate degrees that the AI buildout will require plumbers, electricians, ironworkers, and builders for chip factories, data centers and advanced manufacturing facilities.

"No generation has entered the world with more powerful tools â" or greater opportunities â" than you," he said. "We are all standing at the same starting line. This is your moment to help shape what comes next. So run. Don't walk."

"Every major technological revolution in history created fear alongside opportunity," Huang added. "When society engages technology openly, responsibly, and optimistically, we expand human potential far more than we diminish it."

Full speech: https://www.youtube.com/watch?...

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