Sonos CC200 docking station

From the link: "it’s so useful we included it with every Sonos Controller, complete with an AC Adapter for power. Of course, if you want another Cradle for another room, we’ve made it easy to get an extra."

I believe the first-gen controllers required you to purchase the dock separately (though both controllers can just plug into a wall outlet with the included adapter).

Many of the posters here are ignoring that someone with less knowledge than yourself will have to operate this system. "Running wires" everywhere does nothing for control, especially if you only have volume knobs on the walls, and maybe an IR repeater. And of course, re-wiring a house is not an option for most people. Any proper multiroom audio system in a place with more than two adjacent rooms really requires one or more 2-way panels for control.

This is another beef I have with Sonos, their only control interfaces are wireless, so if you misplace it or kill the battery, you have to run to a computer to control it, instead of a conveniently locaed in-wall touchpanel/keypad (inconvenient if your doorbell of phone rings and you can't pause or tweak the volume).

You can certainly hack something together, but always remember that your momma (or her technical equivalent) should be able to use it.

The Sonos S5 is a speaker/amp/zone player all built into one unit. This technically is a speaker and amplifier, but my post said "separate audio equipment."

I have installed many of these systems, and I second Sonos - could not be easier to set up and use. No need for separate amp/speakers/PC in every room, as they now have a product that is an all-in-one player/speaker. Many of the solutions mentioned here are great ways to go, but I can't think of one that's got a better/easier interface for your wife or similarly tech-challenged household members. Only real caveat is that it won't play DRM-protected audio files - but all the unprotected file formats and internet radio that you can shake a stick at. This beats most of the other solutions because there really is no need for separate audio equipment, including amplifiers.