it depends on what you want to do (Score 1)

All the comments I have read support a CS major if you want to be a programmer, and to a certain extent I agree. But remember what you learn in each degree. In CS you learn the technical aspects of programming. In CIS you learn how Businesses need/use computers. So if you want to come out of college knowing how to write a compiler and other higher technical things, then CS is the way to go. If you want to come out of college knowing how an accounting system works so you can program it, CIS is the way to go. also, your resume isn't just your degree, its your experience. If programming comes easy to you, learn that in your spare time and do the CIS, if business stuff is intuitive then do the CS path.