Comment ISA Server (Score 1) 261
Only application level firewall I have had to work with is Microsoft ISA Server. And from experience I can say that it is too "easy" to use and doesnt offer the features of a real firewall. By using ISA you are expected to use NAT and you cant even do one-to-one IP mappings.
MS can do a lot of "nice" things with ISA, but really ISA is Microsoft's first try at firewalling and you can see it lacks many features a real firewall would have.
Dont be fooled by all the gizmos of ISA Server. Yes it's easy to use, but that doesnt mean everyone and their mother should setup one cause it looks like friendly Windows UI program and is easy.