I can't read the original journal article (boo hoo poor student speaking here) but I'm assuming you're telling us what the original article said - so thank you very very much for that.
I'm a bit confused by the conflation of "organelles" and "vesicles" in the original article though, I assume they're only producing artificial polymer vesicles and not making entire Golgi apparatus or endoplasmic reticulum or something like that.
I have two questions:
Would it be correct to assume that this sort of treatment (inserting enzymes) is more likely to have tangible, significant effects on the body when performed on babies/young children? I imagine you have to treat a lot of cells in adults (and hope they replicate?) in order for your enzymes to have an effect on a tissue...
Also what are some specific benefits of using vesicles that require cell components to *enter* (rather than digest the membrane) instead of releasing them normally? I'm a bit curious.