
The CRIA went after a canadian based P2P distribution site (isohunt), but AFAIK has not gone after 'end-users'. Personally I don't think going after sites like isohunt does much to deter those that will download illegal copies. When 1 site goes down, 5 more come up, hosted in some foreign country.
I'd like to think that if movie & music (and other content) publishers adopted an online distribution mechanism for a fair fee, the industry would flourish instead of flounder. Case in point, last I heard iTunes wasn't doing too bad for itself. It has even allowed indy artists to have a business model that works, instead of trying to get picked up by a publisher, which is not an easy task.
At the end of the day, imho it's a matter of dinosaur business models screaming bloody murder because they're unwilling to adopt to the fast-changing technological world. I applaud the companies that have tried new content distribution models.
I think games are on the forefront, with platforms like steam, or EAs downloader. We just don't need those software boxes lying around anymore. Manuals can be online PDFs or websites easily, convenient, and cheaper to both the publisher & consumer.
Biology grows on you.