Unfortunately, there are a lot of people in those red states that are not pro-business, but are paying the price imposed by those who are. It's the people in government in those places who a) let the polluting companies do whatever, without any kind of preventive or compensatory measures, leading to places like cancer alley, and b) do what they can to keep those people from who are paying the price from having the legal power, or otherwise suppressing what legal power they have, to do anything about the pollution. In some cases, it's also the feds. The D.o.D. has a facility in LA. that "disposes" of all sorts of armaments in open air. There are people in nearby towns that have all sorts of afflictions due to those operations. https://www.propublica.org/art...
In that case, those people have a good idea of what's going on. But they haven't been able to get the support they need.